CAS No. 1235449-52-1
Batch:
Purity:98.88
Chemical Structure
Check the
Ifupinostat
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1235449-52-1 | |
|---|---|---|
| Molecular Formula |
C23H25N9O3S |
|
| Molecular Weight (MW) | 507.57 | |
| SMILES | CNC1=NC=C(C=C1)C2=NC3=C(C(=N2)N4CCOCC4)SC(=C3)CN(C)C5=NC=C(C=N5)C(=O)NO |
BEBT-908 (CUDC-908) is a small-molecule dual inhibitor targeting phosphoinositide 3-kinase alpha (PI3Kα) and histone deacetylases (HDAC). By simultaneously suppressing PI3Kα kinase activity and HDAC deacetylase function, this compound inhibits downstream AKT/mTOR signaling and promotes histone hyperacetylation. These combined actions disrupt survival pathways, suppress cellular proliferation, and trigger apoptotic cell death in targeted cancer cellular models. [1][2]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(197.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.