CAS No. 1224195-72-5
Chemical Structure
Check the
Cu(II)-Elesclomol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | copper [benzenecarbonothioyl(methyl)amino]-[3-[benzenecarbonothioyl(methyl)amino]azanidyl-3-oxopropanoyl]azanide | |
|---|---|---|
| CAS Number | 1224195-72-5 | |
| Molecular Formula |
C19H18CuN4O2S2 |
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| Molecular Weight (MW) | 462.05 | |
| InChIKey | UUSCWIGUMPDFDE-UHFFFAOYSA-L |
Cu(II)-Elesclomol is a copper-chelating complex and a weak inhibitor of DNA topoisomerase I. Treatment with Cu(II)-Elesclomol effectively induces mitochondrial copper-dependent cell death (cuproptosis) as well as apoptosis. In cell models including K562 leukemia cells, this compound promotes DNA double-strand breaks and triggers G1 cell cycle arrest, resulting in potent anticancer activity. [1]
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Note: Technical data last updated: Sep 1, 2026.