CAS No. 68003-38-3
Batch:
Purity:99.93
Chemical Structure
Check the
CTPI-2
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-[(4-chloro-3-nitrophenyl)sulfonylamino]benzoic acid | |
|---|---|---|
| CAS Number | 68003-38-3 | |
| Molecular Formula |
C13H9ClN2O6S |
|
| Molecular Weight (MW) | 356.74 | |
| SMILES | OC(=O)C1=CC=CC=C1N[S](=O)(=O)C2=CC(=C(Cl)C=C2)[N+]([O-])=O | |
| InChIKey | NJTHPOSQGFJTDP-UHFFFAOYSA-N |
Biological Activity
CTPI-2 is an inhibitor of the mitochondrial citrate carrier SLC25A1 with a KD of. By blocking SLC25A1-mediated citrate transport, CTPI-2 impairs mitochondrial metabolism and suppresses downstream glycolysis and PPAR signaling pathways. This disruption limits the metabolic plasticity and self-renewal capacity of cancer stem cells, resulting in reduced cellular proliferation and attenuated tumor stemness phenotypes. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
71 mg/mL
(199.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 35 mg/mL |
| Water | Insoluble |
| DMSO |
71 mg/mL
(199.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 71 mg/mL |
| Water | Insoluble |
| DMSO |
71 mg/mL
(199.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 18 mg/mL |
| Water | Insoluble |
| DMSO |
71 mg/mL
(199.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 18 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
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Note: Technical data last updated: Sep 1, 2026.