CAS No. 2810808-95-6
Batch:
Purity:99.51
Chemical Structure
Check the
CT-996(RO7795081，RG6652）
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 2810808-95-6 | |
|---|---|---|
| Molecular Formula |
C30H31F2N5O5 |
|
| Molecular Weight (MW) | 579.60 |
CT-996 is an orally active, cAMP-biased agonist of the glucagon-like peptide-1 receptor (GLP-1R). Activation of GLP-1R selectively stimulates intracellular cAMP signaling with minimal recruitment of β-arrestin and reduced receptor internalization. This signaling cascade enhances glucose-dependent insulin secretion, suppresses glucagon release, and improves glucose homeostasis, making it valuable for studying metabolic disorders such as type 2 diabetes and obesity. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(172.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(172.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.