Pelabresib (CPI-0610) Mechanism of Action: BET Inhibition in Hematopoietic Stem Cell Research

Pelabresib (CPI-0610) MOA:Targeting BET/NF-κB for Myelofibrosis

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Pelabresib (CPI-0610) is a potent BET inhibitor. It affects NF-κB and SRC/cyclin D1 signaling, and by downregulating these pathways and increasing DNA damage, it inhibits cell viability and promotes apoptosis in cancer cells.

Primary Applications and Mechanism of Action