CP-673451 Mechanism of Action: PDGFR Inhibition in Cancer Cell Research

CP-673451 MOA:Targeting PDGFR/PI3K-Akt Pathway for Oncology Research

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CP-673451 is a selective PDGFR inhibitor. It affects PDGF, Akt, and MEK signaling pathways, and by blocking PDGFR phosphorylation and activating cofilin, it inhibits tumor cell proliferation and migration, and promotes apoptosis.

Primary Applications and Mechanism of Action