CAS No. 591778-68-6
Batch:
Purity:99.93
Chemical Structure
Check the
CP 640186
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | [(3R)-1-[1-(anthracene-9-carbonyl)piperidin-4-yl]piperidin-3-yl]-morpholin-4-ylmethanone | |
|---|---|---|
| CAS Number | 591778-68-6 | |
| Molecular Formula |
C30H35N3O3 |
|
| Molecular Weight (MW) | 485.62 | |
| SMILES | C1CC(CN(C1)C2CCN(CC2)C(=O)C3=C4C=CC=CC4=CC5=CC=CC=C53)C(=O)N6CCOCC6 | |
| InChIKey | LDQKDRLEMKIYMC-XMMPIXPASA-N |
CP 640186 is a potent, isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor that targets rat liver ACC1 and rat skeletal muscle ACC2. By suppressing ACC enzymatic activity, it blocks de novo fatty acid synthesis and enhances mitochondrial fatty acid oxidation, resulting in decreased intracellular malonyl-CoA levels and downstream regulation of metabolic lipid homeostasis. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
97 mg/mL
(199.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 97 mg/mL |
| Water | Insoluble |
| DMSO |
97 mg/mL
(199.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 97 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.