CAS No. 4547-24-4
Batch:
Purity:99.62
Chemical Structure
Check the
Corosolic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 4547-24-4 | |
|---|---|---|
| Molecular Formula |
C30H48O4 |
|
| Molecular Weight (MW) | 472.70 | |
| SMILES | CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1C)C)C(=O)O |
Biological Activity
Corosolic acid is a natural pentacyclic triterpenoid isolated from Lagerstroemia speciosa with anti-cancer and anti-proliferative activities. It modulates multiple intracellular signaling cascades, including the STAT3 and AMPK pathways, leading to the downregulation of pro-survival proteins, induction of apoptosis, and suppression of cancer cell growth across various tumor models. Additionally, corosolic acid regulates cellular glucose uptake and metabolism through activation of insulin receptor signaling. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
48 mg/mL
(101.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 6 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.