CAS No. 32233-40-2
Batch:
Purity:98
Chemical Structure
Check the
Corey Lactone Diol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 32233-40-2 | |
|---|---|---|
| Molecular Formula |
C8H12O4 |
|
| Molecular Weight (MW) | 172.18 | |
| SMILES | C1C(C(C2C1OC(=O)C2)CO)O |
Corey Lactone Diol is a pivotal synthetic intermediate and chiral building block utilized in the preparation of natural prostaglandins and prostaglandin receptor agonists. Prostaglandins synthesized via this scaffold engage specific G protein-coupled receptors, including FP and EP receptors, activating downstream phospholipase C signaling and intracellular calcium mobilization to modulate physiological processes such as intraocular pressure and smooth muscle contraction.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
34 mg/mL
(197.46 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.