CD38 inhibitor 1 (compound 78c) is a potent, selective, and reversible CD38 inhibitor. It affects NAD+ metabolism and SIRT1 signaling by blocking CD38 NADase activity to elevate intracellular NAD+ levels, effectively promoting energy metabolism and ameliorating age-related metabolic dysfunction.
CD38 inhibitor 1 (compound 78c) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for CD38 inhibitor 1 (compound 78c) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.