CAS No. 146501-37-3
Batch:
Purity:99
Chemical Structure
Check the
Complanatoside A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 146501-37-3 | |
|---|---|---|
| Molecular Formula |
C27H30O18 |
|
| Molecular Weight (MW) | 642.52 | |
| SMILES | C1=C(C=C(C(=C1O)OC2C(C(C(C(O2)CO)O)O)O)O)C3=C(C(=O)C4=C(C=C(C=C4O3)O)O)OC5C(C(C(C(O5)CO)O)O)O |
Complanatoside A is a natural flavonol glycoside isolated from Astragalus complanatus that functions as a bioactive plant flavonoid. It modulates intracellular signaling cascades, inhibiting pro-inflammatory cytokine expression via the NF-kB pathway and modulating cellular oxidative stress through the Nrf2 signaling axis. Downstream, these cellular responses attenuate inflammatory reactions, reduce reactive oxygen species production, and exert protective effects against cellular damage in preclinical model systems.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(155.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.