CAS No. 135463-81-9
Batch:
Purity:99.90
Chemical Structure
Check the
Coluracetam
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 135463-81-9 | |
|---|---|---|
| Molecular Formula |
C19H23N3O3 |
|
| Molecular Weight (MW) | 341.40 | |
| SMILES | CC1=C(OC2=NC3=C(CCCC3)C(=C12)NC(=O)CN4CCCC4=O)C |
Coluracetam is a nootropic compound belonging to the racetam family that functions as a high-affinity choline uptake enhancer. It potentiates cholinergic neurotransmission by augmenting choline transportation, leading to increased acetylcholine synthesis in central cholinergic neurons. These downstream pathway alterations contribute to enhanced cognitive function and neuroprotective effects against cholinergic deficits in animal models.
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
68 mg/mL
(199.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 23 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.