Clinical Trials
Numerous clinical trials evaluate collagen across diverse therapeutic applications, encompassing Early Phase 1 through Phase 4 as well as device-focused studies with non-applicable phase designations. Sponsored by various academic and private entities, these trials maintain recruitment statuses ranging from recruiting and completed to terminated or withdrawn. Research targets diverse conditions—including osteoporosis, surgical scars, multiple myeloma, corneal ectasia, and heart failure—with a primary focus on tissue engineering, hemostasis, and structural repair.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT05489510 | WITHDRAWN | Corneal Thinning; Keratoconus |
Vishal Jhanji |
2023-08-15 | PHASE1; PHASE2 |
| NCT07693556 | NOT_YET_RECRUITING | Contracture |
The University of Texas Health Science Center, Houston |
2026-09-01 | EARLY_PHASE1 |
| NCT07693569 | NOT_YET_RECRUITING | Spasticity |
The University of Texas Health Science Center, Houston |
2026-09-01 | EARLY_PHASE1 |
| NCT06724783 | RECRUITING | Tooth Extraction; Tooth Replacement |
Dr. med. dent. Malin Strasding |
2023-06-30 | PHASE4 |
| NCT07756112 | NOT_YET_RECRUITING | Wound Healing |
University of Iowa |
2026-08 | |
| NCT07546279 | RECRUITING | Periodontitis; Bone Defects |
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio |
2025-05-08 | |
| NCT07748871 | NOT_YET_RECRUITING | Tooth Loss / Rehabilitation; Tooth Extraction; Alveolar Bone Loss; Alveolar Ridge Augmentation |
University of Bern |
2026-10 | |
| NCT07225699 | NOT_YET_RECRUITING | Corneal Abrasions |
Milton S. Hershey Medical Center |
2026-11-15 | |
| NCT05426616 | RECRUITING | Alveolar Ridge Enlargement |
University Ghent |
2022-06-01 | |
| NCT07135167 | RECRUITING | Down Syndrome (DS); Keratoconus; Pellucid Marginal Degeneration; Forme Fruste Keratoconus (FFK) |
Woolfson Eye Institute |
2025-08-01 | PHASE3 |
| NCT06269965 | RECRUITING | Cuff Rotator Syndrome |
GCS Ramsay Santé pour l'Enseignement et la Recherche |
2024-04-23 | |
| NCT07743697 | NOT_YET_RECRUITING | Aortic Valve Stenosis; Postoperative Complications; Vascular System Injuries; Hemorrhage |
University Hospital, Basel, Switzerland |
2026-10-01 | |
| NCT07292415 | RECRUITING | This Study is Testing the Use of MatriDerm |
Centre Hospitalier Universitaire de Nice |
2026-02-05 | |
| NCT07740967 | RECRUITING | Cognition; Inflammation Biomarkers; Bone Metabolism Biomarkers; Fatigue Symptom; Sleep; Body Composition Changes; Joint Pain; Quality of Life; Gastrointestinal Comfort; Blood Pressure and Augmentation Index; Muscle Strength; Fatty Acid Blood Profile |
Loughborough University |
2026-05-01 | |
| NCT06270303 | RECRUITING | Periodontitis; Furcation Defects |
Göteborg University |
2025-03-27 | |
| NCT04741607 | RECRUITING | Esthetics |
University Ghent |
2021-01-01 | |
| NCT05699343 | ENROLLING_BY_INVITATION | Peri-Implantitis; Surgery |
Andrea Ravida |
2023-01-30 | |
| NCT07608289 | RECRUITING | Tooth Extraction Site Healing |
University of Ostrava |
2025-01-01 | |
| NCT07130357 | RECRUITING | Achilles Tendon Rupture |
Chinese University of Hong Kong |
2025-12-25 | |
| NCT07032259 | NOT_YET_RECRUITING | Peri-Implantitis |
Loma Linda University |
2026-12 | |
| NCT06885983 | ENROLLING_BY_INVITATION | Bone Healing; Augmentation; Augmentation, Alveolar Ridge |
University of Belgrade |
2025-03-07 | |
| NCT07580495 | RECRUITING | Dehiscence; Tooth Extraction; Alveolar Bone Loss |
Debora Dias |
2026-05-26 | |
| NCT07091448 | NOT_YET_RECRUITING | Alveolar Ridge Preservation |
University of Maryland, Baltimore |
2026-08-01 | PHASE4 |
| NCT07776756 | RECRUITING | Class II Furcation Defect |
University of Medicine and Pharmacy at Ho Chi Minh City |
2026-06-29 | |
| NCT07763808 | RECRUITING | Gingival Recessions, Generalized |
Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors |
2026-09-01 | PHASE2; PHASE3 |
| NCT06503471 | SUSPENDED | Infertility, Female |
Sclnow Biotechnology Co., Ltd. |
2026-12-31 | PHASE1 |
| NCT07386184 | NOT_YET_RECRUITING | Sinus Lift Augmentation |
Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo |
2026-03-19 | |
| NCT06153212 | ENROLLING_BY_INVITATION | Peri-Implantitis |
University of Michigan |
2023-11-02 | |
| NCT01604135 | ACTIVE_NOT_RECRUITING | Keratoconus |
Sahlgrenska University Hospital |
2012-05 | PHASE3 |
| NCT07347236 | NOT_YET_RECRUITING | Fragility Fracture |
Hospital Pengajar Universiti Putra Malaysia |
2026-01 | |
| NCT06834035 | RECRUITING | Epidermolysis Bullosa; Epidermolysis Bullosa Acquisita; Dystrophic Epidermolysis Bullosa; Recessive Dystrophic Epidermolysis Bullosa |
M. Peter Marinkovich |
2025-08-04 | PHASE1; PHASE2 |
| NCT07561203 | RECRUITING | Healthy Adult Male |
Bioiberica |
2026-05-06 | |
| NCT07781917 | NOT_YET_RECRUITING | Diabetic Foot Ulcer (DFU) |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2026-08 | |
| NCT07082244 | RECRUITING | Horizontal Ridge Deficiency |
University of Michigan |
2025-06-01 | |
| NCT07788846 | NOT_YET_RECRUITING | Hemostasis; Surgical Blood Loss; Amputation Stump; Hemorrhage |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2026-09 | |
| NCT07323745 | RECRUITING | Osteoarthritis (OA) of the Knee |
Universiti Sains Malaysia |
2026-05-03 | EARLY_PHASE1 |
| NCT07114523 | RECRUITING | Periodontal Defect |
University of Medicine and Pharmacy at Ho Chi Minh City |
2024-12-01 | |
| NCT04581304 | ACTIVE_NOT_RECRUITING | Bone Loss; Missing Teeth |
Rambam Health Care Campus |
2020-10-15 | |
| NCT04731727 | NOT_YET_RECRUITING | Keratoconus, Unstable |
Kent Wellish MD |
2021-06-30 | EARLY_PHASE1 |
| NCT06038695 | WITHDRAWN | Tooth Extraction; Immediate Implant Placement |
I-Ching Wang |
2025-05 | |
| NCT06722482 | RECRUITING | Ridge Preservation; Allografts; Extraction, Tooth; Xenograft |
University of Rochester |
2023-11-27 | |
| NCT07440186 | NOT_YET_RECRUITING | Patients With Severe Corneal Melting |
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
2026-02-28 | |
| NCT05417776 | RECRUITING | Interstitial Lung Disease |
Massachusetts General Hospital |
2022-09-28 | PHASE2 |
| NCT07577193 | ACTIVE_NOT_RECRUITING | Soft Tissue Atrophy |
Mansoura University |
2025-10-01 | |
| NCT07372911 | RECRUITING | Keratoconus |
Instituto de Oftalmología Fundación Conde de Valenciana |
2025-09-01 | |
| NCT07345195 | NOT_YET_RECRUITING | Erythema; Telangiectasis; Skin Redness |
VIST - Faculty of Applied Sciences |
2026-01 | |
| NCT07450625 | NOT_YET_RECRUITING | Vulvar Lichen Sclerosus; Vulvar Atrophy |
San Gallicano Dermatological Institute IRCCS |
2026-02-20 | |
| NCT05444465 | RECRUITING | Rotator Cuff Injuries |
Smith & Nephew, Inc. |
2022-08-30 | |
| NCT07080177 | NOT_YET_RECRUITING | Missing Teeth |
Cairo University |
2025-09-22 | |
| NCT06235567 | ENROLLING_BY_INVITATION | Keratoconus |
Maanasa Indaram, MD |
2025-04-11 | PHASE1; PHASE2 |
| NCT07446361 | NOT_YET_RECRUITING | Wrinkle Appearance; Skin Quality |
Vichy Laboratoires |
2026-03-01 | |
| NCT07119645 | RECRUITING | Activity-Related Knee Discomfort; Joint Discomfort; Functional Joint Pain; Functional Knee Pain; Knee Acute and Chronic Pain |
Hofseth Biocare ASA |
2025-01-20 | |
| NCT06875830 | RECRUITING | Bone Augmentation; Badly Broken Maxillary Premolars Indicated for Extraction |
Misr International University |
2025-03-06 | |
| NCT05905978 | NOT_YET_RECRUITING | Keratoconus |
Zhongshan Ophthalmic Center, Sun Yat-sen University |
2023-06 | |
| NCT06447844 | ACTIVE_NOT_RECRUITING | Nonterminal Premolar Needing Extraction |
McGuire Institute |
2024-03-28 | |
| NCT06944639 | COMPLETED | Bone Regeneration |
Andrea Ravida |
2025-04-28 | |
| NCT07692009 | COMPLETED | Osteoarthritis (OA) of the Knee |
Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan S. |
2024-01-23 | PHASE4 |
| NCT07605871 | COMPLETED | Skin Condition; Collagen Synthesis |
TCI Co., Ltd. |
2026-05-12 | |
| NCT07683741 | COMPLETED | Periodontitis (Stage 3) |
Hatice Yemenoglu |
2025-02-10 | |
| NCT06570265 | UNKNOWN | Guided Bone Regeneration |
Hyundai Bioland Co., Ltd. |
2024-12-16 | |
| NCT07412067 | NOT_YET_RECRUITING | Apicomarginal Defects |
Postgraduate Institute of Dental Sciences Rohtak |
2026-04-01 | |
| NCT07162207 | ACTIVE_NOT_RECRUITING | Gingival Recession, Localized |
Ain Shams University |
2024-06-01 | |
| NCT05287763 | UNKNOWN | Gingival Recession; Inadequately Attached Gingiva |
The Dental Hospital of Zhejiang University School of Medicine |
2022-04-30 | |
| NCT07048171 | RECRUITING | Apicomarginal Defects |
Postgraduate Institute of Dental Sciences Rohtak |
2025-04-18 | |
| NCT07525128 | ACTIVE_NOT_RECRUITING | Guided Bone Regeneration; Bone Augmentation |
Saint-Joseph University |
2025-03-10 | PHASE4 |
| NCT07413445 | NOT_YET_RECRUITING | Laxity; Skin; Volume Deficiency in the Mid-Face; Wrinkles |
303 Pharma s.r.l. |
2026-03 | |
| NCT06917287 | ACTIVE_NOT_RECRUITING | Knee Osteoarthritis (OA) |
Vedic Lifesciences Pvt. Ltd. |
2025-04-20 | |
| NCT07086482 | RECRUITING | Palate; Wound |
Beirut Arab University |
2025-08-04 | EARLY_PHASE1 |
| NCT07352410 | COMPLETED | Meniscus Tear; Knee Meniscus Injury; Meniscal Repair; Knee Arthroscopy (for Diagnostic or Therapy) |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2026-01-03 | |
| NCT07470112 | ACTIVE_NOT_RECRUITING | Surgical Site Infection (SSI) |
Zagazig University |
2025-05-20 | |
| NCT07335653 | COMPLETED | Injury of Extensor Tendon of Hand; Tendon Adhesions |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2025-12-05 | |
| NCT07241091 | COMPLETED | Peritoneal Surface Malignancy; Postoperative Adhesion; Bowel Obstruction; Wound Complications; Surgical Site Infection After Major Surgery; Ovarian Cancer (OvCa) |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2025-10-20 | |
| NCT07521423 | COMPLETED | Healthy Ageing; Skin Ageing; Oxidative Stress |
Marianna Kapetanou |
2025-10-01 | |
| NCT05632432 | RECRUITING | Ischemic Heart Disease; Ischemic Cardiomyopathy; Heart Failure, Systolic; Heart Failure NYHA Class III; Heart Failure NYHA Class II; Heart Failure NYHA Class IV; Coronary Artery Disease |
Hospital District of Helsinki and Uusimaa |
2024-04-01 | |
| NCT07150442 | COMPLETED | Pelvic Organ Prolapse Vaginal Surgery; Platelet Rich Plasma Injection |
Andalas University |
2025-08-25 | |
| NCT07367165 | COMPLETED | Wound Healing |
Inonu University |
2023-06-01 | |
| NCT07717398 | COMPLETED | Gingival Recession (Miller II) |
Tanta University |
2024-02-24 | |
| NCT07270510 | ACTIVE_NOT_RECRUITING | Extraction Socket Healing; Extraction, Tooth |
Altinbas University |
2025-07-01 | PHASE4 |
| NCT06138236 | RECRUITING | Plantar Fascitis |
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari |
2023-07-01 | EARLY_PHASE1 |
| NCT06703294 | NOT_YET_RECRUITING | Intentional Correction of Forehead Wrinkles (crow's Feet) |
Fiman (Changchun) Pharmaceutical Biotechnology Company Limited |
2024-12-01 | PHASE3 |
| NCT04210596 | ACTIVE_NOT_RECRUITING | Buccal Soft Tissue Profile (BSP) |
University Ghent |
2019-09-01 | |
| NCT06725082 | RECRUITING | Breast Cancer; Collagen Protein |
Peking University People's Hospital |
2024-12-01 | PHASE1 |
| NCT07195396 | COMPLETED | Healthy Women |
Rousselot BVBA |
2025-10-22 | |
| NCT07303543 | RECRUITING | Bariatric Surgery; Muscle Loss |
Medipol University |
2022-08-02 | |
| NCT06172114 | UNKNOWN | Dental Implants; Tooth Extraction; Bone Regeneration |
Mohammed Bin Rashid University of Medicine and Health Sciences |
2024-04-20 | |
| NCT05785949 | TERMINATED | Cartilage Defects |
Geistlich Pharma AG |
2023-03-10 | |
| NCT07174323 | COMPLETED | Prediabetes; Normal Plasma Glucose; Normoglycemia |
INQUIS Clinical Research |
2025-09-08 | |
| NCT06787924 | COMPLETED | Bariatric Surgery; Abdominoplasty; Collagen Synthesis; Skin Physiology; Randomized Controlled Trial; Tissue Remodeling |
General Committee of Teaching Hospitals and Institutes, Egypt |
2025-04-15 | |
| NCT07209020 | RECRUITING | Breast Tumors; Wound Healing; Collagen Wound Dressing |
Maxigen Biotech Inc. |
2025-05-20 | |
| NCT06633211 | NOT_YET_RECRUITING | Bone Substitutes; Tooth Extraction Status Nos |
Adrià Jorba García |
2024-10-15 | |
| NCT06553222 | UNKNOWN | Periodontal Bone Defects |
Al-Azhar University |
2024-11-04 | PHASE3 |
| NCT06519773 | RECRUITING | Immediate Dental Implant |
Tanta University |
2024-07-01 | PHASE1; PHASE2 |
| NCT05695924 | RECRUITING | Lymphedema; Edema |
Fibralign Corporation |
2023-11-01 | |
| NCT06059898 | COMPLETED | Ridge Augmentation |
Botiss Medical AG |
2022-04-08 | |
| NCT06433986 | UNKNOWN | Gingival Recession |
Postgraduate Institute of Dental Sciences Rohtak |
2024-06-01 | |
| NCT07097714 | RECRUITING | Dental Crowding; Gingival Recession; Thin Phenotype |
NMSI DENTMASTER |
2024-06-25 | |
| NCT07046403 | COMPLETED | Diabetic Foot Ulcer (DFU) |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2025-07-05 | |
| NCT06789263 | COMPLETED | Prediabetes; Normoglycemic |
Rousselot BVBA |
2025-01-29 | |
| NCT03943849 | WITHDRAWN | Tooth Loss |
The University of Texas Health Science Center, Houston |
2023-05-01 | |
| NCT06971029 | NOT_YET_RECRUITING | Skin Health; Collagen Supplementation; Growth Factors |
Federal University of São Paulo |
2025-06-09 | PHASE4 |
| NCT06873867 | COMPLETED | Full Thickness Skin Defects; Ulcer |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2025-03-15 | |
| NCT07746466 | COMPLETED | Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3) |
Liaquat National Hospital & Medical College |
2023-06-01 | |
| NCT06900660 | ACTIVE_NOT_RECRUITING | Skin Aging |
Simply Plus Co., Ltd. |
2025-01-13 | |
| NCT06853210 | COMPLETED | Pressure Sore |
Adichunchanagiri Institute of Medical Sciences, B G Nagara |
2025-03-01 | |
| NCT05027295 | UNKNOWN | Keratoconus; Corneal Ectasia |
Cornea and Laser Eye Institute |
2021-07-30 | PHASE3 |
| NCT06724900 | ACTIVE_NOT_RECRUITING | Wrinkles in Decolletage; Pigmentation; Décolleté Wrinkles |
Krystal Biotech, Inc. |
2024-11-20 | PHASE1; PHASE2 |
| NCT06746935 | RECRUITING | Ridge Augmentation; Bone Augmentation |
Cairo University |
2025-01-01 | |
| NCT06831760 | COMPLETED | Venous Leg Ulcers |
Dr Naveen Narayan MS, MCh (Plastic Surgery) |
2025-02-01 | |
| NCT07354178 | COMPLETED | Spinal Tumor; Spinal Injury; Hemostasis; Spinal Stenosis; Spinal Surgery; Intraoperative Bleeding |
DALIM TISSEN Co., Ltd. |
2024-10-22 | |
| NCT07337837 | COMPLETED | Immediate Implant; Vestibular Socket Therapy; Type II Socket |
Alexandria University |
2024-01-01 | |
| NCT07042204 | COMPLETED | Furcation Defects |
Merna Nasser Mohamed Mostafa Ibrahim Elnahas |
2024-01-03 | |
| NCT04905108 | UNKNOWN | Keratoconus; Corneal Ectasia |
Cornea and Laser Eye Institute |
2021-06-02 | PHASE3 |
| NCT04897503 | UNKNOWN | Keratoconus; Corneal Ectasia |
Cornea and Laser Eye Institute |
2021-04-16 | PHASE3 |
| NCT07028606 | ACTIVE_NOT_RECRUITING | Alveolar Bone Resorption |
Al-Azhar University |
2024-05-09 | PHASE1 |
| NCT06264024 | RECRUITING | Keratoconus |
Oslo University Hospital |
2024-02-12 | |
| NCT05407194 | RECRUITING | Patellar Tendinopathy |
Gelderse Vallei Hospital |
2023-04-01 | |
| NCT06689761 | ENROLLING_BY_INVITATION | Collagen Supplementation |
University of Vienna |
2024-11-13 | |
| NCT06252935 | RECRUITING | Guided Tissue Regeneration; Collagen Membrane; Dental Diseases |
Maxigen Biotech Inc. |
2024-07-30 | |
| NCT07302789 | COMPLETED | Skin Ageing; Facial Wrinkles - Rough Texture - Hyperpigmentation; Skin Hydration in Healthy Volunteers |
Bionos Biotech S.L. |
2025-02-26 | |
| NCT05902689 | ACTIVE_NOT_RECRUITING | Alveolar Bone Resorption |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2023-06-15 | |
| NCT06643468 | ENROLLING_BY_INVITATION | Dental Implants; Immediate Implant Soft Tissue Healing; Immediate Implant With Bone Graft |
Mansoura University |
2024-08-14 | |
| NCT06331741 | UNKNOWN | Anterior Cruciate Ligament Injuries; Hallux Rigidus |
I.M. Sechenov First Moscow State Medical University |
2024-03-01 | |
| NCT06945562 | COMPLETED | Tooth Loss |
Faculty of Dental Medicine for Girls |
2024-04-01 | |
| NCT06816953 | ENROLLING_BY_INVITATION | Hemophilia A |
Chulalongkorn University |
2024-04-01 | |
| NCT05489484 | COMPLETED | Rotator Cuff Tendinitis; Syndrome Rotator Cuff; Tendinopathy; Tendinoses, Rotator Cuff; Rotator Cuff Injuries |
Guna S.p.a |
2022-07-04 | |
| NCT04578418 | ACTIVE_NOT_RECRUITING | Tendinopathy |
Bispebjerg Hospital |
2020-09-16 | |
| NCT06579742 | UNKNOWN | Hair Thinning; Hair Loss |
Scale Media Inc |
2024-06-07 | |
| NCT03858036 | UNKNOWN | Keratoconus; Ectasia |
Center for Sight, Sacramento, CA |
2019-03-08 | PHASE3 |
| NCT04802148 | UNKNOWN | Tooth Extraction |
National Taiwan University Hospital |
2021-04-15 | |
| NCT06880185 | COMPLETED | Peri-implant Mucosa Thickness; Peri-implant Mucosa Width; Peri-Implant Tissues |
Ömer Alperen Kırmızıgül |
2023-12-01 | |
| NCT06039839 | UNKNOWN | Soft Tissue Atrophy |
I.M. Sechenov First Moscow State Medical University |
2023-01-17 | |
| NCT07011225 | ACTIVE_NOT_RECRUITING | Collagen Supplementation; Whey Protein; Pulmonary Rehabilitation; COPD - Chronic Obstructive Pulmonary Disease |
Federal University of São Paulo |
2024-08-26 | PHASE4 |
| NCT03050671 | UNKNOWN | Venous Stasis; Deep Venous Thrombosis; Healing Wound |
Karolinska University Hospital |
2017-01-18 | |
| NCT01112072 | UNKNOWN | Keratoconus; Corneal Ectasia |
Cornea and Laser Eye Institute |
2010-04 | PHASE3 |
| NCT01152541 | UNKNOWN | Keratoconus; Corneal Ectasia |
Cornea and Laser Eye Institute |
2010-06 | PHASE3 |
| NCT01464268 | UNKNOWN | Keratoconus; Corneal Ectasia |
Cornea and Laser Eye Institute |
2011-11 | PHASE3 |
| NCT06061315 | COMPLETED | Body Composition; Lean Body Mass; Muscle Strength; Muscle Power |
University of Southern Denmark |
2023-09-15 | |
| NCT06847035 | COMPLETED | Skin Aging |
Shanghai Meifute Biotechnology Co., Ltd |
2024-07-25 | |
| NCT07024186 | COMPLETED | Alveolar Bone Loss; Gingival Recession; Peri-implant Mucositis |
Minia University |
2022-03-17 | |
| NCT07516756 | COMPLETED | Age-related Changes in Skin Appearance and Physiology |
Collagen Research Institute |
2024-08-08 | |
| NCT07345520 | COMPLETED | Gingival Recession, Localized |
Bulent Ecevit University |
2022-12-01 | PHASE3 |
| NCT06308536 | UNKNOWN | Alveolar Ridge Preservation; Concentrated Growth Factor |
The Fourth Affiliated Hospital of Zhejiang University School of Medicine |
2023-05-09 | |
| NCT05572242 | UNKNOWN | Alveolar Ridge Enlargement |
Universidad de los Andes, Chile |
2022-11-01 | |
| NCT01347697 | COMPLETED | Rectal Cancer; Defect of Floor of Lesser Pelvis |
Umeå University |
2011-09-05 | |
| NCT06074276 | UNKNOWN | Collagen Degeneration; Wrinkle; Pigmentation; Elastic Skin |
Integrative Skin Science and Research |
2023-10-04 | |
| NCT07162727 | COMPLETED | Ridge Augmentation |
Dr R Viswa Chandra |
2023-04-13 | |
| NCT05370456 | UNKNOWN | Gingival Recession, Generalized |
University of Turin, Italy |
2022-05-03 | |
| NCT06862505 | COMPLETED | Implant Therapy; Biological Width |
Università degli Studi di Sassari |
2024-02-15 | PHASE4 |
| NCT06229951 | COMPLETED | Osteo Arthritis Knee |
Prince of Songkla University |
2023-11-01 | |
| NCT04667572 | COMPLETED | Keratoconus; Pellucid Marginal Corneal Degeneration; Corneal Degeneration; Corneal Ectasia |
Cornea Associates of Texas |
2021-02-01 | PHASE1 |
| NCT04213885 | COMPLETED | Keratoconus, Unstable; Ectasia Corneal; Bacterial Keratitis |
Eye Specialists of Indiana |
2020-05-04 | PHASE2 |
| NCT03334656 | TERMINATED | Split Thickness Skin Graft; Wound Healing |
Nantes University Hospital |
2018-05-16 | PHASE1; PHASE2 |
| NCT06605768 | COMPLETED | Hair Thinning |
Nutra Harmony LLC |
2024-02-19 | |
| NCT06753084 | COMPLETED | Keratinized Mucosa |
ahmed amer |
2023-11-01 | PHASE1 |
| NCT05568732 | UNKNOWN | Gingival Recession |
Postgraduate Institute of Dental Sciences Rohtak |
2022-10-15 | |
| NCT06523686 | COMPLETED | Alveolar Bone Resorption |
Saint-Joseph University |
2023-01-09 | PHASE2; PHASE3 |
| NCT07212985 | COMPLETED | Implant Dentistry |
Al-Azhar University |
2023-01-05 | |
| NCT05693753 | UNKNOWN | Gingival Recession, Generalized |
University of Turin, Italy |
2023-02-02 | |
| NCT06389539 | Not yet recruiting | Osteoporosis|Inflammation|Aging |
Hebrew SeniorLife|Solarea Bio Inc|Beth Israel Deaconess Medical Center|Tufts University|MaineHealth |
2024-05 | Not Applicable |
| NCT05166395 | Withdrawn | Scar |
University of Miami |
2024-05-01 | Not Applicable |
| NCT06028386 | UNKNOWN | Non-healing Wound; Diabetic Foot Ulcer |
Arch Therapeutics |
2023-08-15 | |
| NCT06321770 | COMPLETED | Facial Wrinkles; Skin Hydration |
Gala Servicios Clinicos S.L. |
2024-03-01 | |
| NCT06615362 | ACTIVE_NOT_RECRUITING | TOOTH EXTRACTION; IMMEDIATE IMPLANT |
Mansoura University |
2022-04-10 | |
| NCT06065774 | COMPLETED | Gingival Recession, Localized |
Mansoura University |
2022-07-17 | |
| NCT06853392 | COMPLETED | Bone Loss; Bone Remodeling Disorder; Bone Resorption |
Faculty of Dental Medicine for Girls |
2023-09-15 | PHASE3 |
| NCT06357351 | UNKNOWN | Gingival Recession |
Mansoura University |
2022-07-01 | |
| NCT06314698 | Not yet recruiting | Multiple Myeloma|Bone Diseases |
RenJi Hospital|Shanghai JMT-Bio Inc. |
2024-04-01 | Phase 3 |
| NCT06257225 | UNKNOWN | Guided Bone Regeneration |
Cairo University |
2024-02-15 | |
| NCT06283173 | COMPLETED | Skin Sensitisation |
Covalon Technologies Inc. |
2024-01-31 | |
| NCT07171411 | COMPLETED | Muscle Hypertrophy; Bone Mineral Density Loss; Resistance Training Adaptation |
Ankara Yildirim Beyazıt University |
2024-01-03 | |
| NCT05330702 | TERMINATED | Tooth Extraction; Immediate Implant Placement |
University of Iowa |
2023-01-17 | |
| NCT05506215 | TERMINATED | Diabetic Foot; Chronic Foot Ulcer; Wound Healing; Foot Ulcer |
PolyNovo Biomaterials Pty Ltd. |
2022-07-10 | |
| NCT06659016 | COMPLETED | Urinary Tract Infection (Diagnosis) |
University of Campania Luigi Vanvitelli |
2023-02-01 | PHASE4 |
| NCT05917925 | UNKNOWN | Pain, Acute; Pain, Chronic; Knee Osteoarthritis; Knee Injuries |
Francisco Javier Martínez Noguera |
2023-04-01 | |
| NCT07153822 | COMPLETED | Lumbar Spinal Stenosis; Lumbar Disc Herniation; Epidural Fibrosis; Postoperative Adhesion |
DALIM TISSEN Co., Ltd. |
2022-12-15 | |
| NCT05569473 | COMPLETED | Intrabony Periodontal Defect |
Postgraduate Institute of Dental Sciences Rohtak |
2022-10-01 | |
| NCT03875833 | WITHDRAWN | Head and Neck Neoplasms; Dysesthesia |
The University of Texas Health Science Center, Houston |
2020-10-09 | |
| NCT05466006 | UNKNOWN | Dental Implants |
University of Turin, Italy |
2022-09-05 | |
| NCT04953572 | UNKNOWN | Cartilage Injury |
Peking University Third Hospital |
2021-08-01 | PHASE1 |
| NCT06194487 | COMPLETED | Skin Condition |
TCI Co., Ltd. |
2023-10-01 | |
| NCT05621252 | COMPLETED | Idiopathic Pulmonary Fibrosis |
Pliant Therapeutics, Inc. |
2022-07-13 | PHASE2 |
| NCT05070871 | COMPLETED | Osteoarthritis; Osteoarthritis, Knee; Osteoarthritis, Hip |
Hofseth Biocare ASA |
2021-09-22 | |
| NCT05887791 | COMPLETED | Healthy; Prediabetic State |
Rousselot BVBA |
2023-06-15 | |
| NCT05916742 | UNKNOWN | Gingival Recession |
Universidade Estadual Paulista Júlio de Mesquita Filho |
2022-04-15 | |
| NCT06140277 | UNKNOWN | Tooth Extraction Status Nos; Bone Augmentation |
Prince Sattam Bin Abdulaziz University |
2023-01-18 | PHASE2 |
| NCT06082271 | COMPLETED | Femoroacetabular Impingement; Hip Arthroscopy; Hip Osteoarthritis; Hydrolyzed Collagen Peptides |
Istituto Ortopedico Rizzoli |
2021-05-28 | |
| NCT04059458 | TERMINATED | Furcation Defects; Periodontal Diseases |
University of Oslo |
2019-10-15 | PHASE4 |
| NCT04527887 | TERMINATED | Dry Eye |
Tufts Medical Center |
2020-09-04 | PHASE4 |
| NCT05563519 | UNKNOWN | Impacted Third Molar Tooth |
Yuzuncu Yil University |
2021-01-15 | |
| NCT05282992 | COMPLETED | Joint Pain |
Bioiberica |
2022-03-03 | |
| NCT06240429 | COMPLETED | Collagen Supplementation; Physical Exercise Training |
University of Sao Paulo |
2023-01-01 | |
| NCT04462575 | COMPLETED | Bone Augmentation |
Cairo University |
2021-04-15 | |
| NCT05722158 | COMPLETED | Healthy Volunteers |
Bionos Biotech S.L. |
2023-08-01 | |
| NCT05212259 | UNKNOWN | Joint Pain |
Vedic Lifesciences Pvt. Ltd. |
2022-10-10 | |
| NCT03735199 | COMPLETED | Bone Resorption After Tooth Extraction |
National Dental Centre, Singapore |
2019-02-28 | |
| NCT05479877 | UNKNOWN | Carious Exposure of Pulp |
Cairo University |
2022-09 | EARLY_PHASE1 |
| NCT05988554 | COMPLETED | Skin Condition |
TCI Co., Ltd. |
2023-06-05 | |
| NCT05985317 | UNKNOWN | Bone Loss, Alveolar |
Cairo University |
2023-01-25 | |
| NCT05282641 | COMPLETED | Glucose Metabolism; Lipid Metabolism |
Maastricht University Medical Center |
2021-05-26 | |
| NCT06275880 | COMPLETED | Gonarthrosis |
Instituto Mexicano del Seguro Social |
2023-04-01 | |
| NCT05730517 | COMPLETED | Dermis Density; Wrinkles; Skin Hydration; Dermis Thickness; Skin Texture; Skin Elasticity |
VIST - Faculty of Applied Sciences |
2023-02-13 | |
| NCT06896097 | COMPLETED | Ridge Preservation |
Faculty of Dental Medicine for Girls |
2022-08-02 | |
| NCT06234813 | COMPLETED | Glanzmann Thrombasthenia |
University Hospital, Bordeaux |
2023-04-06 | |
| NCT06402890 | COMPLETED | Diet; Food; Nutrition |
Liverpool John Moores University |
2021-07-01 | |
| NCT05680857 | COMPLETED | Healthy |
USMARI Research & Innovation Centre |
2022-12-01 | |
| NCT05427279 | COMPLETED | Effect of Food Supplement |
University of California, Davis |
2022-10-05 | |
| NCT05495711 | COMPLETED | Infertility, Female |
Sclnow Biotechnology Co., Ltd. |
2022-08-01 | PHASE1 |
| NCT05486078 | COMPLETED | Greater Trochanteric Pain Syndrome; GTPS - Greater Trochanteric Pain Syndrome; Tendon Disorder; Pertrochanteric Fracture; Gluteal Tendinitis; Gluteal Muscles |
Guna S.p.a |
2021-09-13 | |
| NCT05369780 | UNKNOWN | Pain, Joint |
Sel Sanayi Urunleri Ticaret ve Pazarlama A.S. |
2022-05-15 | |
| NCT05683509 | COMPLETED | Alveolar Ridge Preservation |
Ain Shams University |
2022-05-30 | |
| NCT05789368 | COMPLETED | Skin Condition |
TCI Co., Ltd. |
2023-02-06 | |
| NCT05423535 | WITHDRAWN | Changes in Soft Tissue Height |
University Ghent |
2022-03-06 | |
| NCT05670977 | COMPLETED | Skin Laxity; Skin Lines |
Guangdong HuaPeptides Biotechnology Co., Ltd. |
2023-01-16 | |
| NCT05682092 | COMPLETED | Skin Laxity; Skin Fold |
Shenzhen Precision Health Food Technology Co. Ltd., |
2023-01-16 | |
| NCT05988086 | COMPLETED | Alveolar Cleft |
Tanta University |
2022-10-10 | |
| NCT07285746 | ACTIVE_NOT_RECRUITING | Rotator Cuff Tear |
Hallym University Dongtan Sacred Heart Hospital |
2020-03-02 | |
| NCT06656169 | COMPLETED | Arthritis, Rheumatoid |
Instituto Mexicano del Seguro Social |
2021-01-01 | PHASE1; PHASE2 |
| NCT01789333 | WITHDRAWN | Keratoconus; Ectasia |
Stephen Trokel |
2010-09-01 | |
| NCT05870774 | COMPLETED | Soft Tissue Atrophy |
I.M. Sechenov First Moscow State Medical University |
2021-10-28 | |
| NCT06464718 | COMPLETED | Osteopenia |
Frontier Medical and Dental College, Abbotabad |
2022-06-20 | |
| NCT02921009 | ACTIVE_NOT_RECRUITING | Keratoconus |
McNeel Eye Center |
2016-09-01 | |
| NCT04233892 | UNKNOWN | Infertility, Female, of Uterine Origin; Endometrial Fibrosis |
Yali Hu |
2020-04-29 | PHASE1; PHASE2 |
| NCT04164485 | UNKNOWN | Glottic Insufficiency |
Chinese Academy of Sciences |
2019-07-01 | PHASE1; PHASE2 |
| NCT04843488 | COMPLETED | Bone Regeneration; Dental Implants; Polytetrafluoroethylene |
Urban Regeneration Institute |
2021-04-15 | |
| NCT04678804 | COMPLETED | Gingival Diseases |
University of Parma |
2021-01-20 | PHASE4 |
| NCT04503161 | WITHDRAWN | CSF Leak |
Stanford University |
2021-09 | |
| NCT03294720 | COMPLETED | ACL - Anterior Cruciate Ligament Rupture |
Andrews Research & Education Foundation |
2018-01-08 | PHASE1 |
| NCT05782751 | COMPLETED | GINGIVAL RECESSION |
Tanta University |
2019-01-01 | PHASE4 |
| NCT05936762 | COMPLETED | Osteoarthritis of Knee |
Nextrasearch S.r.l.s. |
2021-08-31 | PHASE4 |
| NCT02680366 | COMPLETED | Infertility; Asherman Syndrome |
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School |
2016-02-22 | |
| NCT04851847 | UNKNOWN | Periodontal Diseases; Intrabony Defects; Guided Tissue Regeneration |
Collagen Matrix |
2021-06-10 | |
| NCT05376657 | COMPLETED | Skin Condition |
TCI Co., Ltd. |
2022-04-01 | |
| NCT03395145 | COMPLETED | Bio-Oss; Mucograft |
Rambam Health Care Campus |
2018-05-27 | |
| NCT04401865 | UNKNOWN | Corneal Ectasia; Keratoconus; Pellucid Marginal Corneal Degeneration |
Colorado Eye Consultants/Cornea Consultants of Colorado |
2020-06-01 | PHASE1; PHASE2 |
| NCT05002634 | UNKNOWN | Health, Subjective |
Chulalongkorn University |
2021-08-05 | |
| NCT05136924 | UNKNOWN | Dry Eye Disease |
Vance Thompson Vision - MT |
2021-12-01 | PHASE2 |
| NCT03205670 | UNKNOWN | Urethral Stricture |
I.M. Sechenov First Moscow State Medical University |
2017-06-01 | EARLY_PHASE1 |
| NCT05174858 | COMPLETED | Tooth Avulsion |
ACTEON Group |
2022-01-25 | |
| NCT05976451 | COMPLETED | Gingival Recession Types One(RT1) |
Ain Shams University |
2020-10-01 | |
| NCT05108272 | UNKNOWN | Hypertrophic Scar |
Foundation University Islamabad |
2021-07-01 | |
| NCT04988412 | COMPLETED | Dermis Density; Wrinkles; Skin Hydration; Trans Epidermal Water Loss (TEWL); Dermis Thickness; Skin Texture; Skin Elasticity |
VIST - Faculty of Applied Sciences |
2021-10-11 | |
| NCT05252962 | COMPLETED | Healthy |
Rousselot BVBA |
2021-11-26 | |
| NCT04673344 | UNKNOWN | Rotator Cuff Tears; Shoulder Surgery |
Rothman Institute Orthopaedics |
2020-12-30 | |
| NCT04338516 | COMPLETED | TEETH EXTRACTION |
Datum Dental LTD |
2019-11-01 | |
| NCT04628520 | UNKNOWN | Mucositis |
Università Vita-Salute San Raffaele |
2018-07-02 | |
| NCT05140161 | UNKNOWN | Nails, Ingrown; Coagulation Defect; Bleeding |
University of Seville |
2021-12-20 | |
| NCT04493073 | UNKNOWN | OCTA |
Asmaa Ahmed Ali Youssif |
2020-12-01 | EARLY_PHASE1 |
| NCT03966794 | UNKNOWN | Spinal Cord Injury |
Chinese Academy of Sciences |
2019-08-01 | PHASE1; PHASE2 |
| NCT02947191 | UNKNOWN | Chronic Nasal Septum Perforation |
Chinese Academy of Sciences |
2016-11 | PHASE1; PHASE2 |
| NCT02510365 | UNKNOWN | Acute Spinal Cord Injury |
Chinese Academy of Sciences |
2015-04 | PHASE1 |
| NCT05020431 | UNKNOWN | Collagen Degeneration |
Alexandria University |
2021-05-15 | |
| NCT06967376 | COMPLETED | Infective Keratitis |
Research Institute of Ophthalmology, Egypt |
2018-05-21 | EARLY_PHASE1 |
| NCT03922503 | UNKNOWN | Intrabony Periodontal Defect |
Cairo University |
2019-09-30 | |
| NCT06236659 | COMPLETED | Diet; Food; Nutrition |
Rob Erskine |
2019-12-01 | |
| NCT06054646 | COMPLETED | Facial Wrinkles - Rough Texture - Hyperpigmentation |
Egyptian Atomic Energy Authority |
2019-05-01 | PHASE2 |
| NCT05122299 | COMPLETED | Dental Implants |
Hams Hamed Abdelrahman |
2021-03-28 | |
| NCT05123898 | UNKNOWN | Soft Tissue Atrophy |
I.M. Sechenov First Moscow State Medical University |
2020-01-14 | |
| NCT06585319 | COMPLETED | COVID 19 |
Materno-Perinatal Hospital of the State of Mexico |
2020-02-01 | PHASE2; PHASE3 |
| NCT03563261 | COMPLETED | Tendon Stiffness With Age |
Liverpool John Moores University |
2019-01-15 | |
| NCT04542668 | COMPLETED | Osteoarthritis, Knee |
Nordic Bioscience A/S |
2020-10-08 | |
| NCT03533933 | UNKNOWN | Gingival Recession |
Elena Ruiz de Gopegui Palacios |
2018-09-01 | |
| NCT04428463 | UNKNOWN | Tympanic Membrane Perforation |
HaEmek Medical Center, Israel |
2020-06-30 | |
| NCT02513303 | COMPLETED | Complication of Renal Dialysis; End Stage Renal Disease; End Stage Kidney Disease; ESRD; Chronic Kidney Failure; Complication of Hemodialysis; Vascular Access Complication; Arteriovenous Fistula |
Vascular Therapies, Inc. |
2015-11 | PHASE3 |
| NCT05425407 | COMPLETED | Exercise; Healthy Male Subjects |
KU Leuven |
2021-04-12 | |
| NCT06812351 | COMPLETED | Randomized Clinical Trial |
Ain Shams University |
2020-03-22 | PHASE1 |
| NCT04019782 | UNKNOWN | Knee Osteoarthritis; Gonarthrosis |
Coordinación de Investigación en Salud, Mexico |
2019-08-01 | PHASE3 |
| NCT05149053 | COMPLETED | Osteoarthritis |
Francisco Jose Rodriguez Velasco |
2020-06-01 | |
| NCT03592849 | COMPLETED | Infertility, Female; Endometrium |
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School |
2018-09-10 | |
| NCT04197128 | UNKNOWN | Alveolar Bone Resorption |
Krishnadevaraya College of Dental Sciences & Hospital |
2019-08-01 | |
| NCT04391725 | UNKNOWN | Periapical Lesion |
Postgraduate Institute of Dental Sciences Rohtak |
2019-12-11 | |
| NCT02786017 | UNKNOWN | Decompensated Cirrhosis |
Chinese Academy of Sciences |
2016-05 | PHASE1; PHASE2 |
| NCT03753880 | UNKNOWN | Bile Leak |
Medical University of Vienna |
2019-10-23 | |
| NCT02745808 | UNKNOWN | Erectile Dysfunction; Type 1 Diabetes Mellitus; Type 2 Diabetes Mellitus |
Chinese Academy of Sciences |
2015-09 | PHASE1 |
| NCT04496856 | COMPLETED | Hip Arthritis; Sarcopenia; Knee Arthritis |
University of Copenhagen |
2020-05-10 | |
| NCT03656068 | COMPLETED | Non-alcoholic Steatohepatitis; Fatty Liver; Fibrosis, Liver; Compensated Cirrhosis |
Pinnacle Clinical Research, PLLC |
2018-12-04 | PHASE2 |
| NCT03746938 | UNKNOWN | Heart Failure With Reduced Ejection Fraction |
Viscofan |
2018-11-13 | PHASE1 |
| NCT04375618 | UNKNOWN | Periodontitis |
SVS Institute of Dental Sciences |
2019-10-01 | PHASE1 |
| NCT05448040 | COMPLETED | Socket Sealing; Free Gingival Graft; Collagen Membrane |
Universidade Salgado de Oliveira |
2018-02-01 | |
| NCT04816110 | COMPLETED | Horizontal Alveolar Bone Defect; Alveolar Bone Loss |
Alexandria University |
2019-04-10 | PHASE2 |
| NCT03464786 | COMPLETED | Tooth Extraction |
Shenzhen Lando Biomaterials Co., Ltd. |
2018-04-03 | |
| NCT05276661 | COMPLETED | Skin Diseases |
Chia Nan University of Pharmacy ＆ Science |
2020-05-18 | |
| NCT04402671 | COMPLETED | Bone Loss |
Saint-Joseph University |
2019-03-01 | |
| NCT04266405 | COMPLETED | Skin Condition |
TCI Co., Ltd. |
2020-03-09 | |
| NCT04357483 | UNKNOWN | Pancreatic Tumor |
Asan Medical Center |
2018-02-01 | PHASE4 |
| NCT03724617 | COMPLETED | Thin Endometrium; Intrauterine Adhesion |
Sir Run Run Shaw Hospital |
2018-10-29 | |
| NCT05751005 | COMPLETED | Pain |
Florida State University |
2018-11-29 | |
| NCT04557943 | COMPLETED | Knee Osteoarthritis |
Hasanuddin University |
2019-09-01 | PHASE4 |
| NCT03457298 | UNKNOWN | Alveolar Ridge Augmentation, Dental Implants |
Rambam Health Care Campus |
2018-11-07 | |
| NCT03003819 | UNKNOWN | Tooth Loss |
McGuire Institute |
2016-10 | |
| NCT03855852 | UNKNOWN | Bone Loss, Alveolar |
Cairo University |
2019-02-01 | |
| NCT03713073 | COMPLETED | Palatal Wound |
The University of Texas Health Science Center, Houston |
2016-10-03 | |
| NCT04224935 | COMPLETED | Immediate Dental Implant Placement; Immediate Implant Placement; Badly Decayed Teeth |
Ain Shams University |
2018-12-01 | |
| NCT03340090 | UNKNOWN | CHD - Coronary Heart Disease |
Medical University of Lodz |
2018-03-20 | |
| NCT04125940 | COMPLETED | Healthy |
University of Memphis |
2019-10-14 | |
| NCT03551145 | UNKNOWN | Peri-Implantitis |
Universidad Complutense de Madrid |
2017-02-01 | PHASE4 |
| NCT03295292 | UNKNOWN | Corneal Scars and Opacities |
L.V. Prasad Eye Institute |
2017-08-01 | PHASE1 |
| NCT04510376 | COMPLETED | Allergic Reaction |
Omeza, LLC |
2019-11-14 | |
| NCT03979157 | COMPLETED | Muscular Diseases |
University of Erlangen-Nürnberg Medical School |
2019-10-14 | |
| NCT03731416 | UNKNOWN | Bone Resorption Disorder |
Cairo University |
2019-10-01 | |
| NCT04213586 | COMPLETED | Exercise; Nutrition Therapy; Resistance Training; Muscle Strength; Hypertrophy |
Universidade Norte do Paraná |
2019-09-01 | |
| NCT03442751 | COMPLETED | Progressive Keratoconus |
Glaukos Corporation |
2018-04-06 | PHASE3 |
| NCT03536143 | COMPLETED | Dystrophic Epidermolysis Bullosa |
Krystal Biotech, Inc. |
2018-05-06 | PHASE1; PHASE2 |
| NCT03680118 | UNKNOWN | Posterior Mandible With Deficient Ridge Height |
Cairo University |
2018-12-15 | |
| NCT04483024 | COMPLETED | Knee Osteoarthritis; Muscle Loss |
Shan May Yong |
2018-12-01 | PHASE1 |
| NCT03697616 | UNKNOWN | Horizontal Deficiecy in Maxillary Arches |
Cairo University |
2018-10-20 | |
| NCT03410745 | COMPLETED | Osteo Arthritis Knee |
Bispebjerg Hospital |
2018-02-21 | |
| NCT03541551 | COMPLETED | Primary Congenital Glaucoma; Developmental Glaucoma; Infantile Glaucoma |
L.V. Prasad Eye Institute |
2018-07-13 | |
| NCT03840681 | UNKNOWN | Guided Bone Regeneration |
Cairo University |
2019-03 | |
| NCT03765125 | COMPLETED | Gingivitis |
Wuerzburg University Hospital |
2018-09-01 | |
| NCT03795792 | COMPLETED | Metabolic Syndrome |
Coordinación de Investigación en Salud, Mexico |
2018-05-06 | |
| NCT03696862 | UNKNOWN | Badly Decayed Upper Anterior Teeth |
Cairo University |
2018-10-20 | |
| NCT03232788 | UNKNOWN | Recession; Periodontal Diseases |
University of Sao Paulo |
2017-04-01 | |
| NCT04267432 | COMPLETED | Osteoarthritis |
TCI Co., Ltd. |
2018-03-28 | |
| NCT05107141 | COMPLETED | Alveolar Ridge Preservation |
Universitat Internacional de Catalunya |
2013-12-09 | |
| NCT03723603 | TERMINATED | Wound |
Medline Industries |
2018-11-09 | |
| NCT03525197 | COMPLETED | Skeletal Muscle Hypertrophy |
McMaster University |
2018-09-01 | |
| NCT04542655 | COMPLETED | Osteoarthritis, Knee |
Nordic Bioscience A/S |
2019-01-07 | |
| NCT05015387 | COMPLETED | Periodontitis, Adult |
Lithuanian University of Health Sciences |
2019-01-09 | PHASE2 |
| NCT03613090 | WITHDRAWN | Root Canal Therapy |
University of Alabama at Birmingham |
2019-04-01 | PHASE2 |
| NCT02090361 | COMPLETED | Skin Graft; Collagen -Elastin Matrix |
University Hospital, Rouen |
2014-06-18 | |
| NCT03811756 | COMPLETED | Dermis Density; Trans Epidermal Water Loss (TEWL); Skin Hydration; Wrinkles; Dermis Thickness |
VIST - Faculty of Applied Sciences |
2018-10-15 | |
| NCT04376060 | COMPLETED | Horizontal Ridge Deficiency |
Saint-Joseph University |
2017-04-04 | |
| NCT03632993 | COMPLETED | Edematous Skin |
Endo USA Inc., a Keenova Therapeutics Company |
2018-09-18 | PHASE2 |
| NCT03664219 | UNKNOWN | Implant Site Reaction |
Cairo University |
2019-01-01 | |
| NCT03749239 | COMPLETED | Collagen Protein |
University of Aarhus |
2018-11-08 | |
| NCT02038257 | UNKNOWN | Vitiligo; Depigmented Scars; Depigmentation |
Henry Ford Health System |
2014-01 | |
| NCT03357705 | COMPLETED | Alveolar Bone Loss |
International Piezosurgery Academy |
2017-10-31 | |
| NCT02686580 | TERMINATED | Anorectal Abscess; Fistula in Ano |
Royal Devon and Exeter NHS Foundation Trust |
2016-02-01 | PHASE3 |
| NCT02644447 | COMPLETED | Premature Ovarian Failure |
Chinese Academy of Sciences |
2015-10 | PHASE1; PHASE2 |
| NCT03357432 | COMPLETED | Collagen Synthesis |
University of California, Davis |
2017-10-21 | |
| NCT04775940 | COMPLETED | Bone Augmentation |
Ain Shams University |
2018-03-01 | |
| NCT03281434 | COMPLETED | Aging |
McMaster University |
2018-01-01 | |
| NCT02174198 | COMPLETED | Tooth Loss |
Columbia University |
2014-01 | |
| NCT03505684 | COMPLETED | Skin Manifestations; Skin Wrinkling |
Pusan National University Yangsan Hospital |
2017-12-24 | |
| NCT02843620 | WITHDRAWN | Joint Discomfort |
Bioiberica |
2018-07 | |
| NCT06280053 | COMPLETED | Venous Ulcers; Bedsores; Diabetic Foot Wound; Burn Wound |
Maxigen Biotech Inc. |
2016-03-02 | |
| NCT03390439 | COMPLETED | Striae Distensae |
Hospital de Clinicas de Porto Alegre |
2017-07-01 | |
| NCT03474874 | COMPLETED | Dermatitis; Allergy; Contact Allergy |
NeXtGen Biologics, Inc. |
2018-02-26 | |
| NCT03191448 | COMPLETED | Tooth Extraction |
The University of Texas Health Science Center at San Antonio |
2015-11-11 | |
| NCT04112888 | COMPLETED | Pelvic Pain |
Althaia Xarxa Assistencial Universitària de Manresa |
2017-05-01 | |
| NCT03994198 | COMPLETED | Muscle Protein Synthesis |
McMaster University |
2017-11-01 | |
| NCT02005861 | COMPLETED | Osteochondritis |
Istituto Ortopedico Rizzoli |
2013-04 | |
| NCT02519881 | COMPLETED | Defect of Articular Cartilage |
Cellontech Co., Ltd. |
2014-02-17 | |
| NCT02990143 | TERMINATED | Glaucoma |
The New York Eye & Ear Infirmary |
2014-01-15 | PHASE2 |
| NCT02685917 | UNKNOWN | Collagen Augmentation |
The Catholic University of Korea |
2016-02 | |
| NCT02672280 | UNKNOWN | Wounds; Diabetic Foot Ulcers; Burns |
South China Research Center for Stem Cell and Regenerative Medicine |
2016-05 | PHASE1; PHASE2 |
| NCT03567148 | COMPLETED | Wound Heal; Graft Pain; Palate; Wound |
Gazi University |
2017-01 | |
| NCT03323567 | COMPLETED | Temporomandibular Disorder |
Medical University of Silesia |
2016-01-10 | EARLY_PHASE1 |
| NCT03037970 | UNKNOWN | Diabetic Foot Ulcers |
Lynch Biologics LLC |
2017-01-30 | PHASE2 |
| NCT02293031 | UNKNOWN | Maxillofacial Bone Defects; Alveolar Bone Atrophy; Jaw Fractures; Maxillofacial Bone Deformities; Bone Neoplasm, Benign; Disorders of Teeth and Jaw |
NextGen Company Limited |
2014-11 | |
| NCT01672814 | COMPLETED | Keratoconus |
Cornea and Laser Eye Institute |
2012-08 | PHASE3 |
| NCT01143389 | COMPLETED | Keratoconus; Post-Refractive Ectasia |
Price Vision Group |
2010-05 | PHASE2 |
| NCT02088970 | TERMINATED | Bacterial Keratitis; Fungal Keratitis |
Nantes University Hospital |
2014-09 | |
| NCT03429569 | UNKNOWN | Keratoconus |
University Hospital, Clermont-Ferrand |
2015-08-12 | PHASE4 |
| NCT03221686 | COMPLETED | Inguinal Hernia |
Lars Nannestad Jorgensen |
2016-02-20 | |
| NCT03354182 | COMPLETED | Furcation Defects |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
2015-07-30 | |
| NCT02009709 | UNKNOWN | Keratoconus; Corneal Ectasia |
Robert Mack, M.D. |
2013-10 | PHASE1 |
| NCT03285737 | COMPLETED | Aging; Muscle Loss |
McMaster University |
2016-03-23 | |
| NCT01458782 | ACTIVE_NOT_RECRUITING | Osteochondritis Dissecans; Osteoarthritis; Cartilage Injury; Osteonecrosis |
University Hospital of North Norway |
2011-10 | |
| NCT03158623 | COMPLETED | Arthroplasty, Replacement |
Salt Lake Orthopedic Clinic |
2016-04-01 | PHASE3 |
| NCT03290638 | COMPLETED | Ridge Deficiency |
Samer Faraj |
2013-10-03 | |
| NCT01873586 | COMPLETED | Degenerative Changes; Stenosis; Spondylosis |
SeaSpine, Inc. |
2012-10 | |
| NCT03399279 | COMPLETED | Intrabony Periodontal Defect |
Ain Shams University |
2014-12-17 | |
| NCT02699580 | COMPLETED | Exotropia or Intermittent Exotropia |
Yonsei University |
2015-09-30 | |
| NCT02449005 | COMPLETED | Chronic Periodontitis |
Aristotle University Of Thessaloniki |
2014-03 | PHASE1; PHASE2 |
| NCT01912638 | COMPLETED | Steroid Induced Glaucoma |
National Centre of Ophthalmology named after academician Zarifa Aliyeva |
2012-07 | PHASE1; PHASE2 |
| NCT02447172 | COMPLETED | Foot Ulcer, Diabetic; Infection |
Innocoll |
2015-06 | PHASE3 |
| NCT02883478 | UNKNOWN | Keratoconus; Corneal Ectasia |
Oslo University Hospital |
2012-08 | PHASE1; PHASE2 |
| NCT02867176 | COMPLETED | Pain |
Instituto de Oftalmología Fundación Conde de Valenciana |
2016-01 | PHASE4 |
| NCT01951768 | COMPLETED | Diabetic Foot Ulcer |
University Hospital, Geneva |
2013-09 | PHASE4 |
| NCT01868620 | TERMINATED | Progressive Keratoconus |
University Hospital, Toulouse |
2013-05 | |
| NCT03833765 | COMPLETED | Gingival Recession |
Roberto Rotundo |
2012-11-28 | |
| NCT02762253 | TERMINATED | Keratoconus |
Nvision Laser Eye Centers |
2012-09 | PHASE2 |
| NCT03506542 | COMPLETED | Glaucoma; Cataract; Wound Heal |
Medical University of Lublin |
2014-06-02 | PHASE2 |
| NCT04243460 | COMPLETED | Tooth Loss |
Medical Innovation Center Wroclaw |
2012-05-01 | |
| NCT02227719 | WITHDRAWN | Bone Gain |
University of Michigan |
2015-09 | PHASE4 |
| NCT02638376 | UNKNOWN | Keratoconus; Post LASIK Keratectasia |
Singapore Eye Research Institute |
2013-03 | PHASE3 |
| NCT02068430 | COMPLETED | Corneal Ulcers |
Stephen Trokel |
2008-11 | PHASE1 |
| NCT02668055 | COMPLETED | Wounds |
Chinese PLA General Hospital |
2012-01 | PHASE1 |
| NCT02330523 | COMPLETED | Tooth Loss |
McGuire Institute |
2014-04 | |
| NCT02818855 | COMPLETED | Gingival Recession |
University of Sao Paulo |
2014-03 | PHASE4 |
| NCT02206009 | COMPLETED | Localized Gingival Recession |
Lauren M. F. Syrowik |
2014-07 | PHASE1 |
| NCT02609295 | COMPLETED | Hypercholesterolemia |
Yonsei University |
2015-02 | PHASE3 |
| NCT02539095 | COMPLETED | Chondromalacia; Osteoarthritis; Traumatic Arthritis |
Cellontech Co., Ltd. |
2014-04 | PHASE4 |
| NCT02328053 | UNKNOWN | Mycotic Corneal Ulcer |
Aravind Eye Care System |
2014-02 | |
| NCT01468571 | UNKNOWN | Pulmonary Hypertension |
Baylor College of Medicine |
2011-07 | PHASE4 |
| NCT01643226 | COMPLETED | Keratoconus |
Glaukos Corporation |
2012-07 | PHASE3 |
| NCT03598634 | COMPLETED | Keratoconus |
University of Molise |
2014-06-01 | |
| NCT01654627 | UNKNOWN | Jaw, Edentulous; Jaw, Edentulous, Partially |
RegeneCure, Ltd. |
2013-04 | PHASE1; PHASE2 |
| NCT02894528 | COMPLETED | Alveolar Process |
University of Sao Paulo |
2013-07 | PHASE4 |
| NCT02067338 | COMPLETED | Morphine |
Mahidol University |
2012-08 | PHASE4 |
| NCT01900964 | COMPLETED | Clinical Efficacy |
University of Louisville |
2012-10 | |
| NCT02242500 | COMPLETED | Gingival Recession |
Enilson Antonio Sallum |
2010-12 | PHASE4 |
| NCT02189447 | COMPLETED | Keratoconus |
The Eye Center and The Eye Foundation for Research in Ophthalmology |
2011-01 | |
| NCT00977405 | TERMINATED | Superficial Surgical Site Infection |
Singapore General Hospital |
2009-09 | PHASE2 |
| NCT02356770 | COMPLETED | Tooth Loss; Soft Tissue Deficiency |
Geistlich Pharma AG |
2012-02 | |
| NCT03419338 | COMPLETED | Maxillary Sinus |
University of Sao Paulo |
2010-03-01 | |
| NCT02008175 | COMPLETED | Keratoconus |
Vasan Eye Care Hospital |
2012-01 | |
| NCT01438788 | COMPLETED | Bethlem Myopathy; Ullrich Congenital Muscular Dystrophy |
Istituto Ortopedico Rizzoli |
2011-10 | PHASE2 |
| NCT01809977 | COMPLETED | Keratoconus |
Isfahan University of Medical Sciences |
2012-07 | PHASE2 |
| NCT01195545 | COMPLETED | Hiatal Hernia |
University of Washington |
2010-05 | |
| NCT01446783 | COMPLETED | Ehlers-Danlos Syndrome, Classic |
Bispebjerg Hospital |
2011-09 | |
| NCT00647569 | COMPLETED | Incisional Hernia; Pelvic Cancer |
University of Aarhus |
2008-04 | PHASE3 |
| NCT01068171 | WITHDRAWN | Diabetic Foot Ulcers |
The University of Texas Health Science Center, Houston |
2010-05 | |
| NCT00719576 | COMPLETED | Articular Cartilage Defect |
Vericel Corporation |
2008-07 | PHASE3 |
| NCT00674661 | COMPLETED | Ectasia |
Glaukos Corporation |
2007-12 | PHASE3 |
| NCT01485211 | COMPLETED | Progressive Keratoconus; Thin Corneas |
Instituto de Olhos de Goiania |
2010-01 | PHASE4 |
| NCT01174420 | UNKNOWN | Open-angle Glaucoma |
Aeon Astron Europe B.V. |
2009-11 | |
| NCT01952301 | COMPLETED | Gingival Diseases |
Perio Health Professionals, PLLC |
2010-11 | |
| NCT01012921 | COMPLETED | Degeneration; Bone |
Institut Straumann AG |
2009-09 | |
| NCT00449098 | UNKNOWN | Glaucoma |
Pro Top & Mediking Company Limited |
2007-01 | PHASE4 |
| NCT00524758 | COMPLETED | Open Angle Glaucoma; Angle Closure Glaucoma; Uveitis Glaucoma; Young Age Glaucoma; Neovascular Glaucoma; High Risk Patient |
Pro Top & Mediking Company Limited |
2007-07 | PHASE3 |
| NCT00478790 | UNKNOWN | Glaucomas; Pterygium |
Pro Top & Mediking Company Limited |
2007-02 | PHASE3 |
| NCT00820040 | TERMINATED | Hernia |
Medtronic - MITG |
2009-07 | PHASE2 |
| NCT00577603 | COMPLETED | Hernia |
Mayo Clinic |
2006-01 | |
| NCT01220024 | COMPLETED | Herniorrhaphy; Postoperative Pain; Inguinal Hernia |
Innocoll |
2010-12-02 | PHASE2 |
| NCT01293045 | COMPLETED | Osteoporosis |
Nealth Sarl |
2010-06 | PHASE1 |
| NCT00777322 | COMPLETED | Keratoconus; Pellucid Marginal Degeneration |
Moorfields Eye Hospital NHS Foundation Trust |
2008-10 | |
| NCT01123057 | UNKNOWN | Corneal Ectasia |
Singapore National Eye Centre |
2008-08 | |
| NCT00890266 | COMPLETED | Keratoconus |
Moorfields Eye Hospital NHS Foundation Trust |
2009-04-22 | |
| NCT00564083 | COMPLETED | Uterine Prolapse |
Atlantic Health System |
2005-12 | |
| NCT00658957 | TERMINATED | Diabetic Foot Ulcer |
Innocoll |
2008-04 | PHASE2 |
| NCT00774228 | COMPLETED | Cataract |
Ocular Therapeutix, Inc. |
2008-10 | |
| NCT00659646 | COMPLETED | Diabetic Foot Ulcer |
Innocoll |
2008-04 | PHASE2 |
| NCT00600925 | COMPLETED | Colorectal Surgery; Surgical Wound Infection |
Innocoll |
2008-01 | PHASE3 |
| NCT00626886 | COMPLETED | Postoperative Pain; Inguinal Hernia |
Innocoll |
2008-03-11 | PHASE2 |
| NCT00435799 | UNKNOWN | Keratoconus |
Ullevaal University Hospital |
2007-02 | PHASE2; PHASE3 |
| NCT01060943 | COMPLETED | Nasolabial Folds |
Cellontech Co., Ltd. |
2008-05 | PHASE3 |
| NCT00749749 | COMPLETED | Pain, Postoperative |
Innocoll |
2008-09-10 | PHASE2 |
| NCT00778089 | TERMINATED | Hypersensitivity |
Suneva Medical, Inc. |
2008-07 | |
| NCT00566943 | COMPLETED | Obesity |
Baxter Healthcare Corporation |
2006-03 | |
| NCT00536302 | COMPLETED | Knee Osteoarthritis (OA) |
GELITA |
2007-03 | PHASE2; PHASE3 |
| NCT00624910 | COMPLETED | Postoperative Pain |
Innocoll |
2007-12-27 | PHASE2 |
| NCT00484055 | COMPLETED | Drug Resistance, Bacterial; Postoperative Wound Infection |
Region Örebro County |
2007-01 | |
| NCT00505336 | COMPLETED | Diastolic Heart Failure |
St Vincent's University Hospital, Ireland |
2006-04 | |
| NCT00321035 | COMPLETED | Glaucoma; Pterygium |
Pro Top & Mediking Company Limited |
2005-12 | PHASE3 |
| NCT00293150 | TERMINATED | Diastolic Heart Failure |
The Cleveland Clinic |
2003-09 | PHASE4 |
| NCT00860912 | COMPLETED | Pelvic Organ Prolapse |
The Cleveland Clinic |
2001-12 | |
| NCT00372034 | COMPLETED | Dry Eye Syndromes |
The University of New South Wales |
2006-07 | |
| NCT00835432 | COMPLETED | Dehiscent Type of Alveolar Bone Defect; One Stage Bone Augmentation |
Charite University, Berlin, Germany |
2005-10 | PHASE4 |
| NCT01547962 | COMPLETED | Gingival Recession |
Organogenesis |
2005-09 | |
| NCT00000401 | COMPLETED | Rheumatoid Arthritis |
University of Tennessee |
1999-07 | PHASE2 |
| NCT00005675 | COMPLETED | Scleroderma; Connective Tissue Diseases |
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
2000-04 | PHASE2 |
| NCT01491477 | TERMINATED | Degenerative Cervical Disc Disease |
Medtronic Spinal and Biologics |
2002-04 | |
| NCT01494493 | TERMINATED | Degenerative Disc Disease |
Medtronic Spinal and Biologics |
2000-09 | |
| NCT01491399 | COMPLETED | Degenerative Cervical Disc Disease |
Medtronic Spinal and Biologics |
1999-09 | |
| NCT01491386 | COMPLETED | Degenerative Disc Disease |
Medtronic Spinal and Biologics |
1998-08 | |
| NCT01491425 | COMPLETED | Degenerative Disc Disease |
Medtronic Spinal and Biologics |
1998-11 | |
| NCT01491373 | COMPLETED | Degeneration of Lumbar Intervertebral Disc |
Medtronic Spinal and Biologics |
1997-01 | |
| NCT00235196 | COMPLETED | Foot Ulcer |
Ethicon, Inc. |
2004-07 | PHASE4 |
| NCT01643252 | WITHDRAWN | Corneal Ectasia |
Glaukos Corporation |
2012-07 | PHASE3 |
| NCT00406822 | TERMINATED | Glaucoma |
Pro Top & Mediking Company Limited |
2006-12 | PHASE3 |
| NCT00001614 | COMPLETED | Arthritis, Juvenile Rheumatoid; Uveitis |
National Eye Institute (NEI) |
1997-07 | PHASE1 |
| NCT00507650 | COMPLETED | Pressure Ulcers |
University of California, San Francisco |
2003-09 | |
| NCT00498992 | UNKNOWN | Dermatologic Complications; Unspecified Adult Solid Tumor, Protocol Specific |
Ingalls Memorial Hospital |
2006-07 |
(data from https://clinicaltrials.gov, updated on 2023-10-05)
Check the
Collagen
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Compliance for Clinical Use
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
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Note: Technical data last updated: Sep 1, 2026.