CAS No. 727-81-1
Batch:
Purity:99.22
Chemical Structure
Check the
Coenzyme Q1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2,3-dimethoxy-5-methyl-6-(3-methylbut-2-enyl)cyclohexa-2,5-diene-1,4-dione | |
|---|---|---|
| CAS Number | 727-81-1 | |
| Molecular Formula |
C14H18O4 |
|
| Molecular Weight (MW) | 250.29 | |
| InChIKey | SOECUQMRSRVZQQ-UHFFFAOYSA-N |
Coenzyme Q1 (CoQ1) is a short-chain ubiquinone derivative that functions as an electron acceptor to measure mitochondrial respiratory chain complex I (NADH:ubiquinone oxidoreductase) activity. Localized within the hydrophobic domain of biological membranes, CoQ1 undergoes reduction during electron transport, exhibiting a notable rotenone-insensitive reduction component. This property facilitates the characterization of mitochondrial electron transfer pathways and cellular energy metabolism in membrane and lipoprotein systems. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
50 mg/mL
(199.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 50 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.