CAS No. 880813-42-3
Batch:
Purity:
Chemical Structure
Check the
CMP-5
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine | |
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| CAS Number | 880813-42-3 | |
| Molecular Formula |
C21H21N3 |
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| Molecular Weight (MW) | 315.41 | |
| InChIKey | YPJMOVVQKBFRNH-UHFFFAOYSA-N |
CMP-5 is a potent and selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5). By inhibiting the methyltransferase activity of PRMT5, CMP-5 selectively blocks symmetric dimethylation of histone H4 arginine 3 (H4R3me2s). This inhibition modulates downstream epigenetic gene expression and suppresses oncogenic signaling pathways, supporting research into Epstein-Barr virus-positive (EBV+) lymphomas and other B-cell non-Hodgkin lymphoma subtypes. [1]
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All in vitro solubility values are batch-tested experimental data (non-literature values).
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.