CAS No. 130-16-5
Batch:
Purity:98.71
Chemical Structure
Check the
Cloxiquine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 5-chloroquinolin-8-ol | |
|---|---|---|
| CAS Number | 130-16-5 | |
| Molecular Formula |
C9H6ClNO |
|
| Molecular Weight (MW) | 179.60 | |
| SMILES | C1=CC2=C(C=CC(=C2N=C1)O)Cl | |
| InChIKey | CTQMJYWDVABFRZ-UHFFFAOYSA-N |
Cloxiquine (5-Chloro-8-quinolinol) is a quinoline derivative that functions as an antibacterial, antifungal, and antituberculosis agent. It disrupts microbial growth and cellular homeostasis by targeting essential bacterial and fungal pathway processes. In addition to its antimicrobial properties, cloxiquine exhibits anti-aging activity by modulating oxidative stress responses and cellular survival pathways, leading to inhibited microbial proliferation and suppressed fungal cellular function.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
35 mg/mL
(194.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 35 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.