CAS No. 22560-50-5
| IUPAC Name | disodium;[dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate | |
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| CAS Number | 22560-50-5 | |
| Molecular Formula |
CH4Cl2O6P0.2Na |
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| Molecular Weight (MW) | 288.86 | |
| SMILES | C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+] | |
| InChIKey | HJKBJIYDJLVSAO-UHFFFAOYSA-L |
Clodronate Disodium is a non-nitrogenous bisphosphonate and antiosteolytic agent that functions as an inhibitor of bone resorption. It is metabolically incorporated into non-hydrolyzable adenosine triphosphate (ATP) analogs within cells, disrupting intracellular energy metabolism and inducing apoptosis in osteoclasts and macrophages. This metabolic pathway impairment effectively reduces osteoclast-mediated bone breakdown and modulates local tissue responses. [1]
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