Cl-amidine is a potent pan-PAD inhibitor. It affects ER stress and EMT signaling by inhibiting PAD activity and reducing protein citrullination, effectively inhibiting NETs formation and tumor cell proliferation.
Cl-amidine IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Cl-amidine Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.