CAS No. 59729-33-8
Batch:
Purity:98.45
Chemical Structure
Check the
Citalopram
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile | |
|---|---|---|
| CAS Number | 59729-33-8 | |
| Molecular Formula |
C20H21FN2O |
|
| Molecular Weight (MW) | 324.39 | |
| InChIKey | WSEQXVZVJXJVFP-UHFFFAOYSA-N |
Citalopram is a selective serotonin reuptake inhibitor (SSRI) that targets the serotonin transporter (SERT). By inhibiting presynaptic SERT, it blocks the reuptake of 5-hydroxytryptamine (5-HT) from the synaptic cleft, thereby elevating extracellular serotonin concentrations and enhancing central serotonergic neurotransmission. This modulation regulates downstream serotonergic signaling pathways that influence mood, emotion, and neuroplasticity in preclinical models. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
65 mg/mL
(200.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 65 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.