Cisplatin Mechanism of Action: ERCC1 Inhibition in Non-Small Cell Lung Cancer Cell Research

Cisplatin MOA:Targeting ERCC1/Nucleotide Excision Repair Pathway for Cisplatin Resistance

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Cisplatin is a cytotoxic DNA crosslinker. It affects p53 and DDR signaling by forming DNA adducts, promoting cell apoptosis.

Primary Applications and Mechanism of Action