SMILES:

CCN1C=C(C(O)=O)C(=O)C2=CN=C(N=C12)N3CCN(CC3)C(=S)NC4=CC(=CC=C4)C(F)(F)F
CID-1517823 Chemical Structure
Chemical Structure
Check the CID-1517823 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid
CAS Number 634175-34-1
Molecular Formula

C22H21F3N6O3S
Molecular Weight (MW) 506.5
SMILES CCN1C=C(C(O)=O)C(=O)C2=CN=C(N=C12)N3CCN(CC3)C(=S)NC4=CC(=CC=C4)C(F)(F)F
InChIKey USYVBPXJSBDUTJ-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 25 mg/mL (49.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.