CAS No. 1510-21-0

Cholesteryl hemisuccinate Chemical Structure
Chemical Structure
Check the Cholesteryl hemisuccinate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxobutanoic acid
CAS Number 1510-21-0
Molecular Formula

C31H50O4

Molecular Weight (MW) 486.73
InChIKey WLNARFZDISHUGS-MIXBDBMTSA-N

Biological Activity

Cholesteryl hemisuccinate is a cholesterol derivative that functions as an inhibitor of DNA polymerases, including DNA polymerase β and DNA polymerase λ, as well as DNA topoisomerase I. By inhibiting these key enzymes involved in DNA replication and repair, the compound disrupts nuclear machinery and cellular division, exhibiting antitumor potential for cancer cell growth research. [1]

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Note: Technical data last updated: Sep 1, 2026.