CAS No. 104-29-0

Batch: Purity:98.86
Chlorphenesin Chemical Structure
Chemical Structure
Check the Chlorphenesin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 104-29-0
Molecular Formula

C9H11ClO3

Molecular Weight (MW) 202.63
SMILES C1=CC(=CC=C1OCC(CO)O)Cl

Biological Activity

Chlorphenesin is a synthetic preservative and cosmetic biocide that exhibits broad-spectrum antimicrobial activity against fungi, yeasts, and bacteria. By inhibiting microbial cell proliferation and compromising cellular membrane integrity, it prevents microbial growth and degradation in formulation matrices. This compound serves to preserve product stability and protect skincare formulations from bacterial and fungal contamination.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 41 mg/mL (202.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 41 mg/mL
Water 10 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.