CAS No. 982-57-0
Batch:
Purity:98
Chemical Structure
Check the
Chloramphenicol sodium succinate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium 4-[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoate | |
|---|---|---|
| CAS Number | 982-57-0 | |
| Molecular Formula |
C15H15Cl2N2O8.Na |
|
| Molecular Weight (MW) | 445.18 | |
| SMILES | C1=CC(=CC=C1C(C(COC(=O)CCC(=O)[O-])NC(=O)C(Cl)Cl)O)[N+](=O)[O-].[Na+] | |
| InChIKey | RPLOPBHEZLFENN-HTMVYDOJSA-M |
Chloramphenicol sodium succinate is a broad-spectrum antibiotic and prodrug form of chloramphenicol that exhibits antibacterial activity by targeting bacterial ribosomes. Upon conversion to its active form, it binds reversibly to the 50S ribosomal subunit at the peptidyl transferase center. This inhibition blocks peptide bond formation during protein translation, disrupting bacterial protein synthesis and ultimately inhibiting bacterial growth across a wide range of Gram-positive and Gram-negative organisms. [1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(199.91 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Chloramphenicol sodium succinate Solubility in DMSO
- Chloramphenicol sodium succinate Stock Solution
- Chloramphenicol sodium succinate Storage
- Chloramphenicol sodium succinate Stability
- Chloramphenicol sodium succinate Molecular Weight
- Chloramphenicol sodium succinate SMILES
- Chloramphenicol sodium succinate Chemical Structure (2D and 3D)
- Chloramphenicol sodium succinate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.