🛡️ Hazard Overview
- GHS Class: GHS05; GHS07; GHS08
- Signal Word: Danger
- Hazard Statements: H302; H314; H317; H318; H334
🧤 PPE Guidelines
- Gloves: Chemical‑resistant gloves suggested
- Eye Protection: Safety goggles suggested
- Respirator: Dust respirator if dust occurs
❄️ Storage
- Storage Temp: -20°C (-4°F) Keep dry
🚑 Emergency First Aid
- For inhalation, skin, eye or ingestion exposure, please refer to full SDS Section 4.
Product identifier
- Product Name: Chloramine-T
- Catalog Number: S6403
- CAS Number: 127-65-1
- IUPAC Name: Benzenesulfonamide, N-chloro-4-methyl-, sodium salt (1:1)
Relevant identified uses and uses advised against
- Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
- Uses advised against: Not for pharmaceutical, household, or other unapproved uses.
Details of the supplier
- Company: Selleck Chemicals
- TollFree: +1 877 796-6397
- Tel: +1 832 582-8158
- Fax: +1 832 582-8590
Emergency telephone number
- Emergency phone #: +1 832 582-8158
2.1 GHS classification in accordance with 29 CFR 1910 (OSHA HCS):
Acute toxicity (oral): Category 4. H302
Skin corrosion: Category 1. H314
Skin sensitization: Category 1. H317
Serious eye damage: Category 1. H318
Respiratory sensitization: Category 1. H334
2.2 GHS Label elements, including precautionary statements
Hazard Pictogram(s):
Signal Word:
Danger
Hazard statement(s):
H302: Harmful if swallowed
H314: Causes severe skin burns and eye damage
H317: May cause an allergic skin reaction
H318: Causes serious eye damage
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s):
Prevention:
P233: Keep container tightly closed.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash hands thoroughly after handling.
P264+P265: Wash hands thoroughly after handling. Do not touch eyes.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection.
P284: [In case of inadequate ventilation] Wear respiratory protection.
Response:
P301+P317: IF SWALLOWED: Get medical help.
P301+P330: IF SWALLOWED: Rinse mouth.
P302+P352: IF ON SKIN: wash with plenty of water.
P302+P361: IF ON SKIN: Take off immediately all contaminated clothing.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P354: IF IN EYES: Immediately rinse with water for several minutes.
P316: Get emergency medical help immediately.
P317: Get emergency medical help.
P321: Specific treatment (see information on this label and safety datasheet)).
P330: Rinse mouth.
P331: Do NOT induce vomiting.
P333+P317: If skin irritation or rash occurs: Get medical help.
P338: Remove contact lenses, if present and easy to do. Continue rinsing.
P342+P316: If experiencing respiratory symptoms: Get emergence medical help immediately.
P354: Immediately rinse with water for several minutes.
P362+P364: Take off contaminated clothing and wash it before reuse.
P363: Wash contaminated clothing before reuse.
Storage:
P403: Store in a well-ventilated place.
P405: Store locked up.
Disposal:
P501: P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Other hazards
None.
3.1 Substances
Product name: Chloramine-T
CAS Number: 127-65-1
PubChem CID: 3641960
Molecular formula: C7H7ClNNaO2S
Molecular weight: 227.64 g/mol
IUPAC name: sodium chloro-(4-methylphenyl)sulfonylazanide
3.2 Mixtures
Not applicable (pure substance).
4.1 Description of first aid measures
Inhalation: Fresh air, rest. Refer for medical attention.
Skin contact: Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eye contact: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion: Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
4.2 Most important symptoms and effects, both acute and delayed
See Section 11 (Toxicological Information).
4.3 Indication of any immediate medical attention and special treatment needed
Treat symptomatically. Contact a poison control center or physician for severe exposure.
5.1 Extinguishing media
Suitable: Water spray, dry chemical, carbon dioxide (CO2), alcohol-resistant foam.
Unsuitable: None known.
5.2 Specific hazards arising from the substance or mixture
Use water spray, powder.
5.3 Advice for firefighters
Wear self-contained breathing apparatus (SCBA) and full protective clothing.
Fight fire from upwind. Cool containers with water spray until fire is extinguished.
Flash point: 192 °C c.c. (trihydrate)
6.1 Personal precautions, protective equipment and emergency procedures
Wear appropriate personal protective equipment (see Section 8).
Avoid breathing dust/vapor. Ensure adequate ventilation.
Evacuate personnel to safe areas. Keep people away from and upwind of spill.
6.2 Environmental precautions
Prevent product from entering drains, waterways, or soil.
Contain spill with inert absorbent material.
6.3 Methods and materials for containment and cleaning up
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
7.1 Precautions for safe handling
Separated from acids and food and feedstuffs.
N-Chloramines should be stored cold and protected from light, water, amines and ammonium compounds, strong acids and bases, and easily oxidized organic materials. /N-Chloramines/
7.2 Conditions for safe storage, including any incompatibilities
Separated from acids and food and feedstuffs.
N-Chloramines should be stored cold and protected from light, water, amines and ammonium compounds, strong acids and bases, and easily oxidized organic materials. /N-Chloramines/
Store away from incompatible materials (see Section 10).
[Note: Specific storage temperature not available in public databases. Refer to supplier Certificate of Analysis (COA) for exact storage conditions.]
8.1 Exposure controls
8.1.1 Occupational exposure limits (OEL)
OSHA PEL: Not established.
ACGIH TLV: Not established.
NIOSH REL: Not established.
No occupational exposure limit values are established for this substance.
Use the lowest feasible exposure level (ALARA principle).
8.1.2 Appropriate engineering controls
Use only in a chemical fume hood or with local exhaust ventilation.
Ensure adequate ventilation to keep airborne concentrations below exposure limits.
8.2 Individual protection measures
8.2.1 Eye/face protection
Wear chemical safety goggles and face shield.
8.2.2 Skin protection
Wear protective gloves. Recommended material: Nitrile rubber.
Wear suitable protective clothing (lab coat).
8.2.3 Respiratory protection
Use NIOSH-approved dust/mist respirator (N95 or higher) if ventilation is inadequate.
8.2.4 Thermal hazards
Not applicable.
9.1 Information on basic physical and chemical properties
a) Appearance: CBI
b) Odor: Slight odor of chlorine
c) Odor threshold: No data available
d) pH: No data available
e) Melting point/freezing point: 170-177 °C decomposes
f) Initial boiling point and boiling range: No data available
g) Flash point: 192 °C c.c. (trihydrate)
h) Evaporation rate: No data available
i) Flammability (solid, gas): No data available
j) Upper/lower flammability or explosive limits: No data available
k) Vapor pressure: No data available
l) Vapor density: No data available
m) Relative density: Density (trihydrate): 1.4 g/cm³
n) Water solubility: Insoluble in benzene, chloroform, and ether; decomposed by alcohol
o) Partition coefficient: n-octanol/water: Log P: No data available
p) Auto-ignition temperature: No data available
q) Decomposition temperature: No data available
r) Viscosity: No data available
s) Explosive properties: No data available
t) Oxidizing properties: No data available
9.2 Other information
Topological Polar Surface Area (TPSA): 43.5 Ų
Complexity: 231
10.1 Reactivity
No specific reactivity hazards identified under normal handling conditions.
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No hazardous reactions under normal conditions.
10.4 Conditions to avoid
Avoid heat, sparks, open flames, direct sunlight, and moisture.
Avoid strong oxidizing agents, strong acids, and strong bases.
10.5 Incompatible materials
The anhydrous material explodes when heated to 175 °C. Mixtures with calcium carbonate + isonitriles explode when warmed.
10.6 Hazardous decomposition products
Thermal decomposition may produce: Carbon monoxide (CO), Carbon dioxide (CO₂), Nitrogen oxides (NOx), Sulfur oxides (SOx), Hydrogen chloride (HCl).
See also Section 5 (Fire-fighting measures) for combustion products.
11.1 Information on toxicological effects
Acute toxicity:
No acute toxicity data available.
Skin corrosion/irritation:
Causes severe skin burns and eye damage (H314).
Serious eye damage/eye irritation:
Causes serious eye damage (H318).
Respiratory or skin sensitization:
May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334).
Germ cell mutagenicity:
No data available.
Carcinogenicity:
No data available.
Reproductive toxicity:
No data available.
Specific target organ toxicity (single exposure):
No data available.
Specific target organ toxicity (repeated exposure):
No data available.
Aspiration hazard:
No data available.
11.2 Additional information
Exposure routes:
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Signs and symptoms of exposure:
Cough. Sore throat. Wheezing.
Redness. Pain.
Redness. Pain.
Nausea. Vomiting. Diarrhoea.
Data source: Hazardous Substances Data Bank (HSDB) via PubChem.
12.1 Toxicity
/AQUATIC SPECIES/ Acute lethal effects of chloramine on eggs and larvae of spotted sea trout given. 48 hr medium tolerance limits for 2 hr old eggs, 10 hr eggs and 1 hr posthatch larvae respectively were 14.14 +/- 1.13, 0.57 +/- 0.28, & 5.75 +/- 3.01 ppm
The substance is toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment.
12.2 Persistence and degradability
No data available.
12.3 Bioaccumulative potential
No data available.
12.4 Mobility in soil
No data available.
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available.
12.6 Other adverse effects
No other adverse ecological effects identified.
13.1 Waste treatment methods
Waste Treatment Methods: Waste material must be disposed of in accordance with national and local regulations. Leave chemicals in original containers and do not mix with other waste. Handle uncleaned containers in the same manner as the product itself.
14.1 UN number
Not regulated as dangerous goods (research quantities typically exempt).
14.2 UN proper shipping name
Not subject to transport regulations (small quantities for research use).
14.3 Transport hazard class(es)
Class 8
14.4 Packing group
Packing group III
14.5 Environmental hazards
Marine pollutant: No (not classified as environmentally hazardous per GHS).
14.6 Special precautions for user
Transport in original packaging. Ensure containers are tightly sealed.
For bulk or commercial quantities, consult applicable transport regulations (DOT, IATA, IMDG).
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
US EPA / TSCA: Subject to EPA TSCA regulations
EU ECHA / REACH: Registered (REACH Active)
SARA 302 Components:
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components:
This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards:
Acute (short-term) health hazard
Massachusetts Right To Know Components:
This material contains components subject to the Massachusetts Right to Know Act. See Section 2 for hazard classification.
Pennsylvania Right To Know Components:
This material contains components subject to the Pennsylvania Right to Know Act. See Section 2 for hazard classification.
New Jersey Right To Know Components:
This material contains components subject to the New Jersey Right to Know Act. See Section 2 for hazard classification.
California Prop. 65 Components:
This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.
Other regulatory listings:
- The Australian Inventory of Industrial Chemicals: Chemical: Benzenesulfonamide, N-chloro-4-methyl-, sodium salt
- California Safe Cosmetics Program (CSCP) Reportable Ingredient: Hazard Traits - Respiratory Toxicity Authoritative List - EC Annex VI Resp. Sens. - Cat. 1 Report - if used as a fragrance or flavor ingredient
15.2 Chemical safety assessment
A chemical safety assessment has not been carried out for this substance.
For research-use-only compounds, no CSA is required under REACH Annex I.
Revision Date: 2026/09/09
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.