CAS No. 6537-80-0
Batch:
Purity:97.31
Chemical Structure
Check the
Chicoric acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 6537-80-0 | |
|---|---|---|
| Molecular Formula |
C22H18O12 |
|
| Molecular Weight (MW) | 474.37 |
Chicoric acid is an orally active dicaffeoyltartaric acid with antioxidant, anti-inflammatory, and antidiabetic properties. It induces ROS generation and triggers mitochondria-dependent apoptosis inT-L1 preadipocytes via the modulation of PIK/Akt and MAPK signaling pathways. Additionally, chicoric acid enhances glucose uptake in skeletal muscle cells and stimulates insulin release, thereby improving insulin sensitivity and ameliorating insulin resistance. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
95 mg/mL
(200.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 24 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.