CAS No. 75621-03-3
Batch:
Purity:99.83
Chemical Structure
Check the
CHAPS
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 75621-03-3 | |
|---|---|---|
| Molecular Formula |
C32H58N2O7S |
|
| Molecular Weight (MW) | 614.88 | |
| SMILES | CC(CCC(=O)NCCC[N+](C)(C)CCC[S]([O-])(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C |
CHAPS is a zwitterionic surfactant and non-denaturing detergent designed for solubilizing membrane proteins while preserving their native functional states. It efficiently disaggregates hydrophobic protein complexes and disrupts lipid-protein interactions without inducing conformational denaturation. Furthermore, CHAPS decreases the sequence specificity of nucleosomes during chromatin assembly and remodeling processes, enabling flexible protein-DNA complex formation in cell-free biochemical assays. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(162.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(162.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.