CAS No. 192322-50-2
Batch:
Purity:99.79
Chemical Structure
Check the
CGP71683 hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 192322-50-2 | |
|---|---|---|
| Molecular Formula |
C26H30ClN5O2S |
|
| Molecular Weight (MW) | 512.07 | |
| SMILES | C1CC(CCC1CNC2=NC3=CC=CC=C3C(=N2)N)CNS(=O)(=O)C4=CC=CC5=CC=CC=C54.Cl |
CGP71683 hydrochloride is a potent, selective, and competitive neuropeptide Y receptor type 5 (Y5 receptor) antagonist displaying a Ki value of 1.3 nM. By blocking Y5 receptor signaling pathways, this compound inhibits neuropeptide Y-induced signaling cascades, effectively suppressing food intake and hyperphagia while regulating neuroendocrine function and energy homeostasis in animal models.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(195.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.