CAS No. 143201-11-0
Batch:
Purity:99.01
Chemical Structure
Check the
Cerivastatin sodium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium (E,3R,5S)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)-3-pyridinyl]-3,5-dihydroxyhept-6-enoate | |
|---|---|---|
| CAS Number | 143201-11-0 | |
| Molecular Formula |
C26H34FNO5.Na |
|
| Molecular Weight (MW) | 482.54 | |
| InChIKey | GPUADMRJQVPIAS-QCVDVZFFSA-M |
Cerivastatin sodium is a synthetic statin and potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (Ki 1.3 nM). By inhibiting HMG-CoA reductase within the cholesterol biosynthesis pathway, it blocks the rate-limiting conversion of HMG-CoA to mevalonate. This pathway inhibition suppresses hepatic cholesterol synthesis and leads to reduced serum low-density lipoprotein cholesterol levels. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
97 mg/mL
(201.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 97 mg/mL |
| Ethanol | 97 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.