CAS No. 75975-70-1

Batch: Purity:98
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Cephradine monohydrate Chemical Structure
Chemical Structure
Check the Cephradine monohydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 75975-70-1
Molecular Formula

C16H19N3O4S.H2O
Molecular Weight (MW) 367.42
SMILES CC1=C(N2C(C(C2=O)NC(=O)C(C3=CCC=CC3)N)SC1)C(=O)O.O

Biological Activity

Cephradine monohydrate is a first-generation beta-lactam cephalosporin antibiotic that displays broad-spectrum bactericidal activity by targeting bacterial penicillin-binding proteins. Inactivation of these transpeptidase enzymes prevents the terminal cross-linking of peptidoglycan chains essential for cell wall synthesis. Consequently, this loss of peptidoglycan network integrity causes osmotic fragility, cell swelling, membrane disruption, and subsequent bacterial lysis.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 4 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.