CAS No. 483-17-0
Chemical Structure
Check the
Cephaeline
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | (1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol | |
|---|---|---|
| CAS Number | 483-17-0 | |
| Molecular Formula |
C28H38N2O4 |
|
| Molecular Weight (MW) | 466.61 | |
| InChIKey | DTGZHCFJNDAHEN-OZEXIGSWSA-N |
Biological Activity
Cephaeline, a desmethyl analog of emetine, is a potent inhibitor of Zika virus (ZIKV) and Ebola virus (EBOV) infection and acts as an inducer of histone H3 acetylation [1][2]. By targeting viral replication and entry pathways, Cephaeline effectively blocks viral infection [1]. Furthermore, Cephaeline-mediated histone H3 acetylation leads to reduced cellular viability, suppressed growth, and impaired migration of mucoepidermoid carcinoma cancer stem cells[1][2].
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Note: Technical data last updated: Sep 1, 2026.