CAS No. 55268-75-2

Batch: Purity:99.46
Cefuroxime Chemical Structure
Chemical Structure
Check the Cefuroxime product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 55268-75-2
Molecular Formula

C16H16N4O8S

Molecular Weight (MW) 424.39

Ordering Information

Biological Activity

Cefuroxime is an orally active, second-generation, broad-spectrum cephalosporin antibiotic possessing stability against β-lactamase degradation. It targets bacterial penicillin-binding proteins, preventing cross-linking during cell wall peptidoglycan synthesis. Disruption of cell wall assembly compromises structural integrity, ultimately triggering osmotic lysis and cell death in a wide range of Gram-positive and Gram-negative bacterial strains. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 85 mg/mL (200.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 3 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.