CAS No. 98753-19-6

Batch: Purity:99.68
Cefpirome sulfate Chemical Structure
Chemical Structure
Check the Cefpirome sulfate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 98753-19-6
Molecular Formula

C22H23N6O5S2.HO4S

Molecular Weight (MW) 612.66
SMILES CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC5=C4CCC5)C(=O)[O-].OS(=O)(=O)O

Ordering Information

Biological Activity

Cefpirome sulfate is a fourth-generation cephalosporin antibiotic that targets penicillin-binding proteins to inhibit bacterial cell wall biosynthesis. By binding to essential penicillin-binding proteins, cefpirome disrupts peptidoglycan cross-linking, leading to cell wall weakening and bacterial cell lysis. It exhibits potent antibacterial activity against a broad spectrum of Gram-negative and Gram-positive pathogens due to rapid outer membrane penetration and stability against many beta-lactamases. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (163.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.