CAS No. 62893-20-3

Batch: Purity:99.15
Cefoperazone sodium Chemical Structure
Chemical Structure
Check the Cefoperazone sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 62893-20-3
Molecular Formula

C25H26N9NaO8S2

Molecular Weight (MW) 667.65
SMILES CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)[O-].[Na+]

Ordering Information

Biological Activity

Cefoperazone sodium is a semi-synthetic, broad-spectrum, third-generation cephalosporin antibiotic that selectively targets bacterial penicillin-binding proteins. By binding to these essential target enzymes, it effectively inhibits the transpeptidation step of peptidoglycan synthesis, thereby disrupting cell wall assembly and triggering bacterial cell lysis. Consequently, cefoperazone sodium displays potent bactericidal activity against a wide variety of Gram-positive and Gram-negative bacterial pathogens.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (149.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.