CAS No. 147816-24-8

Batch: Purity:99.55
Check CoA
Cefcapene Pivoxil Hydrochloride Chemical Structure
Chemical Structure
Check the Cefcapene Pivoxil Hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 147816-24-8
Molecular Formula

C23H29N5O8S2.HCl.H2O
Molecular Weight (MW) 622.11
SMILES CCC=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)OCOC(=O)C(C)(C)C.O.Cl

Biological Activity

Cefcapene pivoxil hydrochloride is an orally active, third-generation cephalosporin prodrug with antibacterial activity. Upon oral administration, it is rapidly ester-hydrolyzed to its active metabolite, cefcapene, which inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This targeted inhibition disrupts peptidoglycan cross-linking in the bacterial cell wall, leading to cell wall degradation, bacterial lysis, and cell death across broad Gram-positive and Gram-negative pathogens.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (160.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.