CAS No. 1207113-88-9
Batch:
Purity:99.91
Chemical Structure
Check the
CCG-100602
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide | |
|---|---|---|
| CAS Number | 1207113-88-9 | |
| Molecular Formula |
C21H17ClF6N2O2 |
|
| Molecular Weight (MW) | 478.82 | |
| SMILES | FC(F)(F)C1=CC(=CC(=C1)C(F)(F)F)C(=O)N2CCCC(C2)C(=O)NC3=CC=C(Cl)C=C3 | |
| InChIKey | MOQCFMZWVKQBAP-UHFFFAOYSA-N |
CCG-0602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling that blocks nuclear translocation of MRTF-A with an ICof. By disrupting MRTF-A/SRF pathway activation, CCG-100602 represses matrix-stiffness and TGF-β-induced fibrogenic activation in human colonic myofibroblasts, leading to downstream reduction of extracellular matrix accumulation and cell-mediated fibrogenesis. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
96 mg/mL
(200.49 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 48 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.