CAS No. 1130067-06-9
Batch:
Purity:99.83
Chemical Structure
Check the
CAY10593 (VU0155069)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[(2S)-1-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]naphthalene-2-carboxamide;hydrochloride | |
|---|---|---|
| CAS Number | 1130067-06-9 | |
| Molecular Formula |
C26H27ClN4O2
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|
| Molecular Weight (MW) | 462.97 | |
| SMILES | CC(CN1CCC(CC1)N2C3=C(C=C(C=C3)Cl)NC2=O)NC(=O)C4=CC5=CC=CC=C5C=C4.Cl | |
| InChIKey | RQULTQQAHGYYDG-LMOVPXPDSA-N |
CAY10593 (VU0155069) is a selective phospholipase D1 (PLD1) inhibitor that impairs human P2X7 receptor activation. By selectively inhibiting PLD1 enzymatic activity, CAY10593 modulates phospholipase signaling pathways and suppresses the downstream generation of phosphatidic acid. This targeted inhibition disrupts key lipid signaling networks, leading to impaired P2X7 receptor-mediated functional responses and altered cellular phenotypes. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
15 mg/mL
(32.39 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.