CAS No. 179463-17-3
Batch:
Purity:99.98
Chemical Structure
Check the
Caspofungin (MK-0991) Acetate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | acetic acid;N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-21-(2-aminoethylamino)-3-[(1R)-3-amino-1-hydroxypropyl]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl]-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexazatricyclo[22.3.0.09,13]heptacosan-18-yl]-10,12-dimethyltetradecanamide | |
|---|---|---|
| CAS Number | 179463-17-3 | |
| Molecular Formula |
C52H88N10O15.2C2H4O2 |
|
| Molecular Weight (MW) | 1213.42 | |
| SMILES | CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(C(NC(=O)C2C(CCN2C(=O)C(NC(=O)C(NC(=O)C3CC(CN3C(=O)C(NC1=O)C(C)O)O)C(C(C4=CC=C(C=C4)O)O)O)C(CCN)O)O)NCCN)O.CC(=O)O.CC(=O)O | |
| InChIKey | OGUJBRYAAJYXQP-LLXMLGLCSA-N |
Caspofungin Acetate (MK-0991) is an echinocandin lipopeptide antifungal agent that functions as a potent β-1,3-glucan synthase inhibitor. By selectively inhibiting the synthesis of 1,3-β-D-glucan, an essential structural component of the fungal cell wall, it disrupts cell wall integrity and leads to severe osmotic instability, cell lysis, and cell death in Candida and Aspergillus species.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(82.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 50 mg/mL |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(82.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 50 mg/mL |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(82.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(82.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(82.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Caspofungin (MK-0991) Acetate Clinical Trials
- Caspofungin (MK-0991) Acetate Solubility in DMSO
- Caspofungin (MK-0991) Acetate Storage
- Caspofungin (MK-0991) Acetate Stability
- Caspofungin (MK-0991) Acetate Molecular Weight
- Caspofungin (MK-0991) Acetate SMILES
- Caspofungin (MK-0991) Acetate Chemical Structure (2D and 3D)
- Caspofungin (MK-0991) Acetate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.