CAS No. 1139-30-6
Batch:
Purity:99.79
Chemical Structure
Check the
Caryophyllene oxide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1139-30-6 | |
|---|---|---|
| Molecular Formula |
C15H24O |
|
| Molecular Weight (MW) | 220.35 | |
| SMILES | CC1(CC2C1CCC3(C(O3)CCC2=C)C)C |
Caryophyllene oxide is a naturally occurring oxygenated sesquiterpene compound exhibiting significant anti-inflammatory and anticarcinogenic activities. It suppresses both constitutive and inducible STAT3 activation as well as NF-kB signaling pathways by inhibiting upstream kinases and STAT3 phosphorylation. Downstream, this cascade blockade downregulates anti-apoptotic protein expression, impairs tumor cell proliferation, and induces caspase-mediated apoptotic cell death across multiple human cancer models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
44 mg/mL
(199.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 44 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.