Cariprazine HCl

For research use only.

Catalog No.S5849 Synonyms: RGH-188

1 publication

Cariprazine HCl Chemical Structure

CAS No. 1083076-69-0

Cariprazine (RGH-188), a novel second-generation antipsychotic, is a D3-preferring dopamine D2/D3 receptor partial agonist.

Selleck's Cariprazine HCl has been cited by 1 publication

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Biological Activity

Description Cariprazine (RGH-188), a novel second-generation antipsychotic, is a D3-preferring dopamine D2/D3 receptor partial agonist.

Protocol

References

Solubility (25°C)

In vitro DMSO 5 mg/mL (10.77 mM)
Water 3 mg/mL (6.46 mM)
Ethanol '4 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 463.87
Formula

C21H33Cl3N4O

CAS No. 1083076-69-0
Storage powder
in solvent
Synonyms RGH-188
Smiles CN(C)C(=O)NC1CCC(CC1)CCN2CCN(CC2)C3=C(C(=CC=C3)Cl)Cl.Cl

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04382885 Recruiting Drug: Cariprazine Autism Spectrum Disorder Allergan June 26 2020 Phase 1
NCT01626859 Completed Drug: MP-214 3mg|Drug: MP-214 6mg|Drug: MP-214 9mg Schizophrenia Mitsubishi Tanabe Pharma Corporation May 2012 Phase 2|Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID