CAS No. 3505-38-2
Batch:
Purity:99.72
Chemical Structure
Check the
CarbinoxaMine Maleate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | (Z)-but-2-enedioic acid;2-[(4-chlorophenyl)-pyridin-2-ylmethoxy]-N,N-dimethylethanamine | |
|---|---|---|
| CAS Number | 3505-38-2 | |
| Molecular Formula |
C16H19ClN2O.C4H4O4 |
|
| Molecular Weight (MW) | 406.86 | |
| SMILES | CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O | |
| InChIKey | GVNWHCVWDRNXAZ-BTJKTKAUSA-N |
Biological Activity
Carbinoxamine maleate is a histamine H1 receptor antagonist with antihistaminic and anticholinergic properties. By competitively blocking histamine H1 receptors, carbinoxamine suppresses histamine-mediated signaling pathways, resulting in reduced vascular permeability, inhibited smooth muscle contraction, and attenuated allergic responses. Furthermore, its anticholinergic activity modulates muscarinic receptor signaling to suppress cellular activation and downstream mediator release.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
81 mg/mL
(199.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 81 mg/mL |
| Ethanol | 81 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.