CAS No. 57775-29-8
Batch:
Purity:98.81
Chemical Structure
Check the
Carazolol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 57775-29-8 | |
|---|---|---|
| Molecular Formula |
C18H22N2O2 |
|
| Molecular Weight (MW) | 298.38 | |
| SMILES | CC(C)NCC(COC1=CC=CC2=C1C3=CC=CC=C3N2)O |
Carazolol is a potent, non-selective beta-adrenergic receptor blocking agent that binds with high affinity to beta-adrenergic receptors. By binding to beta-adrenergic receptors, it disrupts G protein-coupled receptor activation and suppresses downstream cAMP signaling. This blockade inhibits sympathomimetic signal transduction pathways, resulting in reduced beta-adrenergic responsiveness and modulation of cardiovascular and smooth muscle cellular functions. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
60 mg/mL
(201.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 60 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.