CAS No. 135531-86-1
Batch:
Purity:99.89
Chemical Structure
Check the
Camalexin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-(1H-indol-3-yl)-1,3-thiazole | |
|---|---|---|
| CAS Number | 135531-86-1 | |
| Molecular Formula |
C11H8N2S |
|
| Molecular Weight (MW) | 200.26 | |
| SMILES | C1=CC=C2C(=C1)C(=CN2)C3=NC=CS3 | |
| InChIKey | IYODIJVWGPRBGQ-UHFFFAOYSA-N |
Camalexin is an indole-derived phytoalexin isolated from cruciferous plants with antimicrobial, antifungal, and anticancer activities. It induces intracellular reactive oxygen species (ROS) production, leading to oxidative stress and cell damage. Increased ROS levels trigger mitochondrial apoptotic signaling pathways, resulting in the inhibition of cancer cell proliferation and cell death. Camalexin also disrupts fungal and bacterial cellular integrity to exert antimicrobial effects. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
40 mg/mL
(199.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 40 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.