CAS No. 20633-67-4

Batch: Purity:99.93
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Calycosin-7-O-beta-D-glucoside Chemical Structure
Chemical Structure
Check the Calycosin-7-O-beta-D-glucoside product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 20633-67-4
Molecular Formula

C22H22O10
Molecular Weight (MW) 446.40
SMILES COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)OC4C(C(C(C(O4)CO)O)O)O)O

Ordering Information

Biological Activity

Calycosin-7-O-beta-D-glucoside is a natural isoflavone glycoside isolated from Astragalus species that exhibits antioxidant, anti-inflammatory, and neuroprotective biological activities. It modulates key cellular signaling cascades, suppressing the NF-kB inflammatory pathway and reducing the production of pro-inflammatory cytokines. Furthermore, Calycosin-7-O-beta-D-glucoside mitigates oxidative stress by scavenging reactive oxygen species and preserving mitochondrial function, thereby protecting neuronal and cardiovascular cells from ischemic injury.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 89 mg/mL (199.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.