CAS No. 346691-38-1
Batch:
Purity:99.67
Chemical Structure
Check the
C-170
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-(4-butylphenyl)-5-nitrofuran-2-carboxamide | |
|---|---|---|
| CAS Number | 346691-38-1 | |
| Molecular Formula |
C15H16N2O4 |
|
| Molecular Weight (MW) | 288.30 | |
| SMILES | CCCCC1=CC=C(NC(=O)C2=CC=C(O2)[N+]([O-])=O)C=C1 | |
| InChIKey | QMVOHFICEFYHMK-UHFFFAOYSA-N |
C-is a covalent small-molecule inhibitor of stimulator of interferon genes (STING) that efficiently targets both human and murine STING. Covalently modifying STING at Cys91 blocks its activation-induced palmitoylation, preventing assembly into multimeric complexes at the Golgi apparatus and recruitment of downstream signaling factors. Consequently, C-suppresses STING-dependent inflammatory cytokine production and attenuates pathological features of autoinflammatory disease. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
58 mg/mL
(201.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 14 mg/mL |
| Water | Insoluble |
| DMSO |
58 mg/mL
(201.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 14 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.