CAS No. 345651-04-9
Batch:
Purity:99.32
Chemical Structure
Check the
BVDV IN-1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-[4-(2-phenylquinazolin-4-yl)piperazin-1-yl]ethanol | |
|---|---|---|
| CAS Number | 345651-04-9 | |
| Molecular Formula |
C20H22N4O |
|
| Molecular Weight (MW) | 334.41 | |
| SMILES | OCCN1CCN(CC1)C2=C3C=CC=CC3=NC(=N2)C4=CC=CC=C4 | |
| InChIKey | DPFKMYSBAMEGQK-UHFFFAOYSA-N |
Biological Activity
BVDV IN-1 is a non-nucleoside inhibitor targeting bovine viral diarrhea virus (BVDV) RNA-dependent RNA polymerase (RdRp) with an EC50 value of. By binding directly to an allosteric pocket on the viral RdRp enzyme, it disrupts assembly and activity of the viral replication complex. This inhibition halts downstream viral RNA synthesis and genome replication, thereby suppressing viral propagation and preventing virus-induced cytopathic effects. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
67 mg/mL
(200.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 34 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.