CAS No. 149-64-4

Batch: Purity:99.99
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Butylscopolamine Bromide Chemical Structure
Chemical Structure
Check the Butylscopolamine Bromide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [(1R,2R,4S,5S)-9-butyl-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate bromide
CAS Number 149-64-4
Molecular Formula

C21H30NO4.Br
Molecular Weight (MW) 440.37
SMILES CCCC[N+]1(C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4)C.[Br-]
InChIKey HOZOZZFCZRXYEK-HNHWXVNLSA-M

Ordering Information

Biological Activity

Butylscopolamine Bromide is a peripherally acting quaternary ammonium anticholinergic agent that functions as a competitive antagonist of muscarinic acetylcholine receptors. By inhibiting muscarinic receptor-mediated cholinergic signaling, it blocks parasympathetic activation of smooth muscle tissue. This inhibition suppresses contractile responses, effectively alleviating spasmodic activity in gastrointestinal, biliary, and genitourinary smooth muscles while exhibiting minimal central nervous system penetration. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 88 mg/mL (199.83 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 88 mg/mL
Ethanol 88 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.