CAS No. 152580-79-5
Batch:
Purity:99.91
Chemical Structure
Check the
Buddlejasaponin IVb
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 152580-79-5 | |
|---|---|---|
| Molecular Formula |
C48H78O18 |
|
| Molecular Weight (MW) | 943.12 | |
| SMILES | CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC5=C6CC(CCC6(C(CC54C)O)CO)(C)C)C)C)OC7C(C(C(C(O7)CO)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)O |
Buddlejasaponin IVb is a natural triterpenoid saponin isolated from Pleurospermum kamtschaticum that exhibits anti-inflammatory and cytotoxic activities. It modulates cellular signaling pathways to attenuate the production of pro-inflammatory mediators, including nitric oxide and prostaglandin E2. Additionally, Buddlejasaponin IVb inhibits cancer cell proliferation and decreases cell viability, highlighting its potential in anti-inflammatory and oncological research.
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(106.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
100 mg/mL
(106.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.