CAS No. 25561-30-2

Batch: Purity:
BSTFA-TMCS Chemical Structure
Chemical Structure
Check the BSTFA-TMCS product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 25561-30-2
Molecular Formula

C8H18F3NOSi2

Molecular Weight (MW) 257.40
SMILES C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C

Ordering Information

Biological Activity

BSTFA-TMCS is a widely used derivatizing and silylation reagent in chromatography and metabolomic analysis. It functions by reacting with active hydrogen-containing functional groups, including alcohols, amines, carboxylic acids, phenols, and steroids, to yield volatile trimethylsilyl derivatives. This chemical modification enhances the thermal stability and volatility of polar biological molecules, facilitating their separation, identification, and quantitative detection in gas chromatography-mass spectrometry applications. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.