CAS No. 980-71-2

Batch: Purity:99.99
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Brompheniramine hydrogen maleate Chemical Structure
Chemical Structure
Check the Brompheniramine hydrogen maleate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine;(Z)-but-2-enedioic acid
CAS Number 980-71-2
Molecular Formula

C16H19BrN2.C4H4
Molecular Weight (MW) 435.31
SMILES CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O
InChIKey SRGKFVAASLQVBO-BTJKTKAUSA-N

Ordering Information

Biological Activity

Brompheniramine hydrogen maleate is a propylamine-class histamine H1 receptor antagonist. By competitively binding to histamine H1 receptors, it blocks endogenous histamine signaling pathways, suppressing downstream allergic inflammation and vasodilation. Additionally, brompheniramine functions as a moderately effective anticholinergic agent, demonstrates antidepressant-like serotonin reuptake inhibition, and undergoes oxidative hepatic metabolism by cytochrome P450 enzymes. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 87 mg/mL (199.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 46 mg/mL
Ethanol 18 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.